Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600119 | 0.92 | ALDH1A1 (0.52) | MAPTSMN1; SMN2RAB9AHTTMEN1 | |
| SCHEMBL16599909 | 0.88 | SIRT6 (0.46) | MAPTSMN1; SMN2RAB9AHTTTP53 | |
| SCHEMBL16600104 | 0.88 | CYP1A2 (0.52) | MAPTSMN1; SMN2RAB9AHTTMAPK1 | |
| SCHEMBL16609018 | 0.86 | SIRT6 (0.47) | MAPTSMN1; SMN2RAB9AHTTMEN1 | |
| SCHEMBL16599996 | 0.86 | KMT2A (0.48) | MAPTSMN1; SMN2TP53KMT2AALDH1A1 | |
| SCHEMBL16600133 | 0.85 | WDR5 (0.47) | MAPTSMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL1890774 | 0.85 | SIRT6 (0.61) | MAPTSMN1; SMN2RAB9AHTTMAPK1 | |
| SCHEMBL20976884 | 0.85 | MAPT (0.51) | MAPTSMN1; SMN2RAB9AMAPK1TP53 | |
| SCHEMBL16608992 | 0.83 | RAB9A (0.53) | MAPTSMN1; SMN2RAB9ATP53MEN1 | |
| SCHEMBL16600000 | 0.83 | DRD2 (0.47) | KMT2AALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015048306-A1 | NOVEL AGENTS TARGETING CYP51 | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-04-02 | — | — | WO | disclosed |