Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762271 | 0.76 | SGMS2 (0.33) | CYP1A2 | |
| SCHEMBL7312533 | 0.75 | GABRA1 (0.35) | L3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL6546758 | 0.75 | CALM1 (0.46) | HTR2AHRH1L3MBTL1DRD2DRD1 | |
| SCHEMBL10782398 | 0.73 | CALM1 (0.44) | HTR2AHRH1L3MBTL1DRD2DRD1 | |
| SCHEMBL135667 | 0.73 | MAPK1 (0.56) | CYP3A4TSHRMAPTMAPK1 | |
| SCHEMBL8815094 | 0.72 | BCL2 (0.45) | HTR2AHRH1L3MBTL1DRD2DRD1 | |
| SCHEMBL29470998 | 0.72 | BCL2 (0.45) | HTR2AHRH1L3MBTL1DRD2DRD1 | |
| SCHEMBL8322110 | 0.72 | HTR2A (0.47) | HTR2AHRH1L3MBTL1DRD2DRD1 | |
| SCHEMBL2636152 | 0.71 | PTGS2 (0.34) | CYP2C9BCL2L1HPGDSMN1; SMN2MAPT | |
| SCHEMBL10900432 | 0.70 | HTR2A (0.41) | HTR2AHRH1L3MBTL1DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052498-A1 | 3,7-DIAZABICYCLO[3.3.1]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS | Council of Scientific & Industrial Research (IN) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015044951-A1 | 3,7-DIAZABICYCLO[3.3.1 ]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-04-02 | — | — | WO | disclosed |