SCHEMBL16601568

SCHEMBL16601568

C=C1C(C)C(C)C(=O)N1c1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ADRA2A P08913 1/20 0.31
ACLY P53396 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9975769 0.87 ADRA2A (0.36) MEN1HPGDKMT2ASMN1; SMN2NPSR1
SCHEMBL11762036 0.71 TSHR (0.47) MEN1KMT2ASMN1; SMN2NPSR1
SCHEMBL16601565 0.66 MAOA (0.49) MEN1KMT2A
SCHEMBL465067 0.65 MGLL (0.47) MEN1HPGDKMT2ASMN1; SMN2NPSR1
SCHEMBL9188786 0.63 KMT2A (0.44) MEN1HPGDKMT2ASMN1; SMN2NPSR1
SCHEMBL12367662 0.63 MAPK1 (0.46) MEN1HPGDKMT2ANPSR1
SCHEMBL13179873 0.62 ADAM17 (0.58)
SCHEMBL1902124 0.62 CA1 (0.45)
SCHEMBL9977566 0.62 MAPK1 (0.38) MEN1HPGDKMT2ASMN1; SMN2NPSR1
SCHEMBL2661119 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993699-B2 Photosensitive resin composition for microlens NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-03-31 US disclosed