SCHEMBL16601922

SCHEMBL16601922

Cc1ccc(N(C)C(=O)N(C)c2ccc(CO)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
ALOX15 P16050 1/20 0.43
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
TSHR P16473 1/20 0.40
NAMPT P43490 1/20 0.37
HSP90AA1 P07900 1/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18843564 0.92 PPARG (0.39) ALDH1A1SMN1; SMN2ALOX15TSHRMAPT
SCHEMBL9705583 0.92 PPARG (0.39) ALDH1A1SMN1; SMN2ALOX15TSHRMAPT
SCHEMBL12550524 0.86 ALDH1A1 (0.53) ALDH1A1KDM4EHTTRAB9ASMN1; SMN2
SCHEMBL7567915 0.85 MGLL (0.37) ALDH1A1SMN1; SMN2ALOX15TSHR
SCHEMBL12550510 0.81 HSP90AA1 (0.49) ALDH1A1HTTRAB9ASMN1; SMN2HSP90AA1
SCHEMBL7563538 0.80 LMNA (0.43) ALDH1A1HTTTSHRMEN1KMT2A
Trimethylammonium SCHEMBL9858163 0.80 IDO1 (0.46) ALDH1A1TSHR
SCHEMBL18840274 0.79 ALDH1A1 (0.55) ALDH1A1KDM4EHTTTSHR
SCHEMBL25188378 0.79 PPARG (0.42) ALDH1A1RAB9AALOX15TSHRMEN1
SCHEMBL8924930 0.79 POLB (0.50) ALDH1A1KDM4ERAB9ASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993204-B2 Electrophotographic photosensitive member, method for producing the same, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed