SCHEMBL944019

SCHEMBL944019

CC(C)c1ccccc1SSc1ccccc1C(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.48
GABRB2 P47870 2/20 0.48
GABRG2 P18507 2/20 0.44
GABRB3 P28472 2/20 0.44
FAAH O00519 2/20 0.44
LMNA P02545 2/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
GABRB1 P18505 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
HTR2C P28335 1/20 0.44
GABRA5 P31644 1/20 0.44
GABRA3 P34903 1/20 0.44
HTR2B P41595 1/20 0.44
GABRA2 P47869 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601927 0.87 KMT2A (0.64) GABRA1GABRB2GABRG2GABRB3FAAH
SCHEMBL21032249 0.86 GABRA1 (0.41) GABRA1GABRB2GABRG2GABRB3FAAH
SCHEMBL30389926 0.84 GABRA1 (0.48) GABRA1GABRB2GABRG2GABRB3FAAH
SCHEMBL4808650 0.84 GABRA1 (0.48) GABRA1GABRB2GABRG2GABRB3FAAH
SCHEMBL21031568 0.83 GABRA1 (0.39) GABRA1GABRB2GABRG2GABRB3FAAH
SCHEMBL5594562 0.82 GABRA1 (0.46) GABRA1GABRB2GABRG2GABRB3FAAH
SCHEMBL24499178 0.80 GABRA1 (0.44) GABRA1GABRB2GABRG2GABRB3FAAH
SCHEMBL10408276 0.80 CYP2D6 (0.43) GABRA1GABRB2LMNACYP1A2CYP3A4
SCHEMBL18897631 0.80 GABRA1 (0.44) GABRA1GABRB2GABRG2GABRB3FAAH
SCHEMBL5594557 0.80 GABRA1 (0.44) GABRA1GABRB2GABRG2GABRB3FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1171960-C diffusion film for diffusion plate 精碟科技股份有限公司 2004-10-20 CN claimed
CN-1401714-A diffusion film for diffusion plate JINGDIE SCI & TECH CO LTD (CN) 2003-03-12 CN claimed
US-8987516-B2 Process for producing arylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2015-03-24 US disclosed
EP-2468722-B1 Process for producing arylsulfur halotetrafluorides UBE INDUSTRIES (JP) 2014-10-01 EP disclosed
EP-2468721-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2014-02-26 EP disclosed
EP-2468720-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-11-27 EP disclosed
EP-2468719-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-10-16 EP disclosed
EP-2137144-B1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES UBE INDUSTRIES (JP) 2013-07-31 EP disclosed
CN-103197363-A Scratch-proof optics diffusion film and preparation method thereof HUBEI AEROSPACE CHEMICAL TECHNOLOGY INST 2013-07-10 CN disclosed
US-8399720-B2 Methods for producing fluorinated phenylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2013-03-19 US disclosed
US-20110306798-A1 Methods for Producing Arylsulfur Pentafluorides UBE INDUSTRIES, LTD. (JP) 2011-12-15 US disclosed
US-7820864-B2 2,3,4,5,6-pentafluorophenylsulfur pentafluoride; as intermediates for introduce sulfur pentafluoride groups into various commercial organic molecules; liquid crystals, fungicides, herbicides, and insecticides IM&T RESEARCH, INC. (US) 2010-10-26 US disclosed
US-20100130790-A1 Methods for Producing Fluorinated Phenylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-05-27 US disclosed
US-20100076215-A9 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-03-25 US disclosed
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-02-04 US disclosed
WO-2010014665-A1 METHODS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T RESEARCH, INC. (US) 2010-02-04 WO disclosed
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2009-11-19 US disclosed
US-7592491-B2 Process for producing arylsulfur pentafluorides IM&T RESEARCH, INC. (US) 2009-09-22 US disclosed
CN-1171960-C diffusion film for diffusion plate 精碟科技股份有限公司 2004-10-20 CN disclosed
CN-1401714-A diffusion film for diffusion plate JINGDIE SCI & TECH CO LTD (CN) 2003-03-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA GABRA1 755/4885GABRB2 1556/4885GABRG2 616/4885
US-20100130790-A1 Methods for Producing Fluorinated Phenylsulfur Pentafluorides BRPF1, SFXN3, SLFN12 GABRA1 983/4885GABRB2 1311/4885GABRG2 1314/4885
US-20100076215-A9 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA GABRA1 755/4885GABRB2 1556/4885GABRG2 616/4885
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA GABRA1 755/4885GABRB2 1556/4885GABRG2 616/4885
US-20110306798-A1 Methods for Producing Arylsulfur Pentafluorides PFAS, ARSA, HDHD5 GABRA1 1160/4885GABRB2 1875/4885GABRG2 967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.