Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601936 | 0.99 | TDP1 (0.34) | GSTP1GSTM2ACHEBCHETDP1 | |
| SCHEMBL17069545 | 0.85 | LMNA (0.35) | LMNACYP1A2DRD3SCN1ASLC6A3 | |
| SCHEMBL8739105 | 0.85 | LMNA (0.41) | ACHEHRH3MAPK1LMNACYP1A2 | |
| SCHEMBL16140052 | 0.85 | LMNA (0.41) | ACHEHRH3MAPK1LMNACYP1A2 | |
| SCHEMBL16601930 | 0.72 | RAB9A (0.39) | ACHETDP1HRH3MAPK1LMNA | |
| SCHEMBL16601934 | 0.71 | ACHE (0.37) | GSTP1GSTM2ACHEHTR2CLTA4H | |
| SCHEMBL16601928 | 0.71 | ACHE (0.37) | GSTP1GSTM2ACHEHTR2CLTA4H | |
| SCHEMBL16601932 | 0.70 | ACHE (0.35) | GSTP1GSTM2ACHERETHTR2C | |
| SCHEMBL9829525 | 0.69 | MAPT (0.53) | TDP1LMNAPOLBRAB9A | |
| SCHEMBL10820595 | 0.68 | NAAA (0.51) | ACHEHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8992991-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |