SCHEMBL1660561

SCHEMBL1660561

CCCCCCCC(C)(C)CO

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
TSHR P16473 2/20 0.46
ALDH1A1 P00352 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
GGPS1 O95749 6/20 0.43
THRB P10828 1/20 0.42
FDPS P14324 9/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
FFAR1 O14842 1/20 0.41
CPT2 P23786 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CES2 O00748 1/20 0.40
LPAR1 Q92633 1/20 0.40
LPAR3 Q9UBY5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21061014 1.00 LMNA (0.46) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL706771 1.00 LMNA (0.46) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL1021722 1.00 LMNA (0.46) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL12264009 1.00 LMNA (0.46) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL1021089 1.00 LMNA (0.46) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL6327464 1.00 LMNA (0.46) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL6322452 1.00 LMNA (0.46) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL22748594 1.00 LMNA (0.46) LMNATSHRALDH1A1HSD17B10MEN1
SCHEMBL1028937 0.97 SMN1; SMN2 (0.43) LMNATSHRALDH1A1HSD17B10MEN1
Bromide SCHEMBL28217329 0.95 LMNA (0.42) LMNATSHRALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995003381-A1 THICKENED HYPOCHLORITE DETERGENT COMPOSITIONS WITH IMPROVED CLEANING PERFORMANCE THE PROCTER & GAMBLE COMPANY (US) 1995-02-02 WO claimed
EP-0635568-A1 Thickened hypochlorite detergent compositions with improved cleaning performance THE PROCTER & GAMBLE COMPANY (US) 1995-01-25 EP claimed
US-20140234364-A1 TOTAL SYNTHESIS AND IMMUNOLOGICAL EVALUATION OF SACCHARIDE MOIETIES OF THE LIPOPOLYSACCHARIDE FROM NEISSERIA MENINGITIDIS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2014-08-21 US disclosed
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-20130131169-A1 COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-05-23 US disclosed
US-8377458-B2 Cooling sensation agent composition, sensory stimulation agent composition and use of the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-02-19 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
US-20110081393-A1 COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME TAKASAGO INTERNATIONAL CORPORATION 2011-04-07 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed
US-20070219196-A1 AMIDE SUBSTITUTED IMIDAZOPYRIDINES, IMIDAZOQUINOLINES, AND IMIDAZONAPHTHYRIDINES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2007-09-20 US disclosed
WO-1995003381-A1 THICKENED HYPOCHLORITE DETERGENT COMPOSITIONS WITH IMPROVED CLEANING PERFORMANCE THE PROCTER & GAMBLE COMPANY (US) 1995-02-02 WO disclosed
EP-0635568-A1 Thickened hypochlorite detergent compositions with improved cleaning performance THE PROCTER & GAMBLE COMPANY (US) 1995-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 LMNA 1708/4885TSHR 2479/4885ALDH1A1 520/4885
US-20070219196-A1 AMIDE SUBSTITUTED IMIDAZOPYRIDINES, IMIDAZOQUINOLINES, AND IMIDAZONAPHTHYRIDINES IL2, IL4, IFNG LMNA 4342/4885TSHR 1198/4885ALDH1A1 1449/4885
US-20110081393-A1 COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME TRPA1, TRPV1, TRPM4 LMNA 1727/4885TSHR 3786/4885ALDH1A1 685/4885
US-20130131169-A1 COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME TRPA1, TRPV1, TRPM4 LMNA 1727/4885TSHR 3786/4885ALDH1A1 685/4885
US-20140234364-A1 TOTAL SYNTHESIS AND IMMUNOLOGICAL EVALUATION OF SACCHARIDE MOIETIES OF THE LIPOPOLYSACCHARIDE FROM NEISSERIA MENINGITIDIS FUT5, DAD1, STT3B LMNA 1379/4885TSHR 1319/4885ALDH1A1 4188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.