Sugi Predict

Sugi Predict / Compounds / SCHEMBL166086

SCHEMBL166086

SCHEMBL166086

O=[N+]([O-])c1cccc2[nH]ncc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOS1 P29475 6/20 1.00
▸ TDO2 P48775 2/20 0.60
▸ TDP1 Q9NUW8 2/20 0.56
▸ KDM4E B2RXH2 2/20 0.56
▸ MEN1 O00255 2/20 0.56
▸ CYP1A2 P05177 2/20 0.56
▸ CYP3A4 P08684 2/20 0.56
▸ MAPT P10636 2/20 0.56
▸ TSHR P16473 2/20 0.56
▸ CYP2C19 P33261 2/20 0.56
▸ NOS2 P35228 2/20 0.56
▸ BLM P54132 2/20 0.56
▸ KMT2A Q03164 2/20 0.56
▸ THRB P10828 1/20 0.56
▸ HPGD P15428 1/20 0.56
▸ APEX1 P27695 1/20 0.56
▸ NOS3 P29474 1/20 0.56
▸ RECQL P46063 1/20 0.56
▸ SMN1; SMN2 Q16637 1/20 0.56
▸ NPSR1 Q6W5P4 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30410422 1.00 NOS1 (1.00) NOS1TDO2TDP1KDM4EMEN1
Acetic Acid SCHEMBL27632907 0.91 NOS1 (0.82) NOS1TDO2TDP1KDM4EMEN1
SCHEMBL10594462 0.87 NOS1 (0.77) NOS1TDO2TDP1KDM4EMEN1
SCHEMBL2323565 0.86 NOS1 (0.74) NOS1TDO2TDP1KDM4EMEN1
SCHEMBL15796947 0.85 NOS1 (0.74) NOS1TDO2TDP1KDM4EMEN1
SCHEMBL27632861 0.84 NOS1 (0.70) NOS1TDO2TDP1KDM4EMEN1
SCHEMBL25291457 0.80 NOS1 (0.65) NOS1TDO2TDP1KDM4EMEN1
SCHEMBL31690218 0.79 NOS1 (0.66) NOS1TDO2TDP1KDM4EMEN1
SCHEMBL331389 0.79 NOS1 (0.66) NOS1TDO2TDP1KDM4EMEN1
SCHEMBL10595301 0.78 NOS1 (0.63) NOS1TDO2TDP1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 698 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119223101-A Environment-friendly airport bird repellent bomb 中北大学 2024-12-31 — — CN claimed
WO-2023092175-A1 NOVEL P2X7 RECEPTOR ANTAGONISTS THE UNIVERSITY OF SYDNEY (AU) 2023-06-01 — — WO claimed
CN-106399484-B Double-bubble fluorescent probe and application and kit thereof 中国人民解放军第三军医大学第一附属医院 2020-03-24 — — CN claimed
US-20260070887-A1 AMIDE OR UREA COMPOUND SHENZHEN ZHONGGE BIOLOGICAL TECH CO LTD (CN) 2026-03-12 — — US disclosed
US-20260014147-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2026-01-15 — — US disclosed
US-20250388599-A1 TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE GENENTECH INC (US) 2025-12-25 — — US disclosed
US-20250388577-A1 METTL3 INHIBITORY COMPOUNDS STORM THERAPEUTICS LTD (GB) 2025-12-25 — — US disclosed
US-20250325677-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2025-10-23 — — US disclosed
US-20250320205-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2025-10-16 — — US disclosed
US-20250320206-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2025-10-16 — — US disclosed
EP-4628486-A1 AMIDE OR UREA COMPOUND Shenzhen Zhongge Biological Technology Co., Ltd. (CN) 2025-10-08 — — EP disclosed
US-5356761-A Adding replenisher of hydroxy and mercapto substituted pyrimidines; minimizing silver stain and sludge FUJI PHOTO FILM CO., LTD. (JP) 1994-10-18 — — US disclosed
US-5298372-A Automatic development FUJI PHOTO FILM CO., LTD. (JP) 1994-03-29 — — US disclosed
EP-0507284-A1 Development of silver halide photosensitive material and developer FUJI PHOTO FILM CO., LTD. (JP) 1992-10-07 — — EP disclosed
US-4636456-A EXPOSURE, SILVER HALIDE EMULSIONS, HYDROQUINONE OR ESTER OR CARBONATE, DEVELOPMENT INHIBITORS FUJI PHOTO FILM CO., LTD. (JP) 1987-01-13 — — US disclosed
US-4171975-A MAGENTA COUPLER AND AN AMIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-10-23 — — US disclosed
US-4153460-A Light-sensitive silver halide color photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD (JP) 1979-05-08 — — US disclosed
US-4146630-A HYPOTENSIVE AGENTS BOEHRINGER MANNHEIM GMBH (DE) 1979-03-27 — — US disclosed
US-4096333-A NITROSATION OF A 2-METHYLACETANILIDE TENNECO CHEMICALS, INC. (US) 1978-06-20 — — US disclosed
US-3988347-A NITROSATION OF A 2-METHYL-ACETANILIDE WITH SODIUM NITRITE TENNECO CHEMICALS, INC. (US) 1976-10-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325677-A1 STAT6 DEGRADERS STAT6, STAT5B, STAT1 NOS1 1758/4885TDO2 1526/4885TDP1 1466/4885
US-20250388577-A1 METTL3 INHIBITORY COMPOUNDS METTL3, RNMT, TPMT NOS1 550/4885TDO2 199/4885TDP1 725/4885
US-20250320205-A1 STAT6 DEGRADERS STAT6, STAT1, STAT5B NOS1 1924/4885TDO2 1584/4885TDP1 1186/4885
US-20260014147-A1 STAT6 DEGRADERS STAT6, NCOR1, CBR1 NOS1 648/4885TDO2 791/4885TDP1 1465/4885
US-20260070887-A1 AMIDE OR UREA COMPOUND KIF18A, KIF18B, KIF23 NOS1 4139/4885TDO2 3840/4885TDP1 3083/4885
US-20250320206-A1 STAT6 DEGRADERS STAT6, STAT5B, STAT1 NOS1 1758/4885TDO2 1526/4885TDP1 1466/4885
US-20250388599-A1 TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE PIK3C2B, PIK3C2A, PIK3R1 NOS1 1992/4885TDO2 3158/4885TDP1 2491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.