SCHEMBL16610041

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31371260	0.88	TUBB1 (0.51)	TSHRLMNACYP3A4GAANFKB1
	SCHEMBL19750509	0.83	MET (0.42)	LMNAALDH1A1ALOX5GAAALOX15
	SCHEMBL8126304	0.82	PDCD1 (0.40)	PTPN1SHBGNOS2ALDH1A1
	SCHEMBL22398472	0.82	MAOB (0.43)	MAPK1TDP1MAOB
	SCHEMBL2497156	0.82	DRD2 (0.39)	MAPK1SHBGLMNAALDH1A1GAA
	SCHEMBL358600	0.82	ALDH1A1 (0.56)	TSHRALDH1A1CYP3A4GAATDP1
	SCHEMBL30168383	0.82	ALDH1A1 (0.56)	TSHRALDH1A1CYP3A4GAATDP1
	SCHEMBL18310146	0.80	DRD2 (0.41)	MAPK1LMNAALDH1A1CYP3A4ALOX5
	SCHEMBL12191689	0.80	CRHBP (0.41)	MAPK1ALDH1A1GAAMAOB
	SCHEMBL16599423	0.80	THRB (0.35)	TSHRMAPK1LMNAAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.