SCHEMBL16611571

SCHEMBL16611571

COC(=O)[C@@H]1CC[C@@H](NOCc2ccccc2)CN1C(=O)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 5/20 0.41
ALDH1A1 P00352 2/20 0.40
TSHR P16473 2/20 0.40
CYP3A4 P08684 1/20 0.40
MMP2 P08253 1/20 0.39
PDK2 Q15119 4/20 0.38
PDK1 Q15118 2/20 0.38
PDK3 Q15120 2/20 0.38
PDK4 Q16654 2/20 0.38
CPB1 P15086 1/20 0.38
GAA P10253 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
KLK5 Q9Y337 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16611573 1.00 FKBP1A (0.41) FKBP1AALDH1A1TSHRCYP3A4MMP2
Hydrochloric Acid SCHEMBL16611802 0.99 FKBP1A (0.41) FKBP1AALDH1A1TSHRCYP3A4MMP2
Hydrochloric Acid SCHEMBL16611804 0.99 FKBP1A (0.41) FKBP1AALDH1A1TSHRCYP3A4MMP2
SCHEMBL9949645 0.91 FKBP1A (0.39) FKBP1AALDH1A1TSHRPDK2PDK1
SCHEMBL9949649 0.91 FKBP1A (0.39) FKBP1AALDH1A1TSHRPDK2PDK1
SCHEMBL1248268 0.90 ALDH1A1 (0.42) ALDH1A1TSHRPDK2PDK1PDK3
SCHEMBL1248269 0.90 ALDH1A1 (0.42) ALDH1A1TSHRPDK2PDK1PDK3
SCHEMBL1248266 0.90 ALDH1A1 (0.42) ALDH1A1TSHRPDK2PDK1PDK3
Hydrochloric Acid SCHEMBL17956540 0.89 ALDH1A1 (0.41) ALDH1A1TSHRPDK2PDK1PDK3
SCHEMBL2819701 0.88 FKBP1A (0.36) FKBP1AALDH1A1TSHRCYP3A4PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250059191-A1 CRYSTALLINE FORMS OF DIAZABICYCLOOCTANE DERIVATIVE AND PRODUCTION PROCESS THEREOF MEIJI SEIKA PHARMA CO., LTD. (JP) 2025-02-20 US disclosed
US-12221443-B2 Crystalline forms of diazabicyclooctane derivative and production process thereof MEIJI SEIKA PHARMA CO., LTD. (JP) 2025-02-11 US disclosed
US-12103928-B2 Processes for preparing a diazabicyclooctane compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2024-10-01 US disclosed
US-20230331724-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND MEIJI SEIKA PHARMA CO., LTD. (JP) 2023-10-19 US disclosed
US-11731971-B2 Processes for preparing a diazabicyclooctane compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2023-08-22 US disclosed
US-20220348578-A1 CRYSTALLINE FORMS OF DIAZABICYCLOOCTANE DERIVATIVE AND PRODUCTION PROCESS THEREOF MEIJI SEIKA PHARMA CO., LTD. (JP) 2022-11-03 US disclosed
US-11414417-B2 Crystalline forms of diazabicyclooctane derivative and production process thereof MEIJI SEIKA PHARMA CO., LTD. (JP) 2022-08-16 US disclosed
US-20210371419-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND MEIJI SEIKA PHARMA CO., LTD. (JP) 2021-12-02 US disclosed
US-11117896-B2 Processes for preparing a diazabicyclooctane compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2021-09-14 US disclosed
CN-111153903-A Crystal of diazabicyclooctane derivative, preparation method and application thereof, and pharmaceutical composition 明治制果药业株式会社 2020-05-15 CN disclosed
US-10131665-B2 Processes for producing diazabicyclooctane compounds MEIJI SEIKA PHARMA CO., LTD. (JP) 2018-11-20 US disclosed
US-20180258089-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND MEIJI SEIKA PHARMA CO., LTD. (JP) 2018-09-13 US disclosed
US-10023573-B2 Beta-lactamase inhibitor and process for preparing the same MEIJI SEIKA PHARMA CO., LTD. (JP) 2018-07-17 US disclosed
US-20170233393-A1 BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME MEIJI SEIKA PHARMA CO., LTD. (JP) 2017-08-17 US disclosed
US-9708320-B2 β-lactamase inhibitor and process for preparing the same MEIJI SEIKA PHARMA CO., LTD. (JP) 2017-07-18 US disclosed
US-20160272641-A1 CRYSTALLINE FORMS OF DIAZABICYCLOOCTANE DERIVATIVE AND PRODUCTION PROCESS THEREOF MEIJI SEIKA PHARMA CO., LTD. (JP) 2016-09-22 US disclosed
US-20160024090-A1 BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME MEIJI SEIKA PHARMA CO., LTD. (JP) 2016-01-28 US disclosed
US-9181250-B2 Beta-lactamase inhibitor and process for preparing the same MEIJI SEIKA PHARMA CO., LTD. (JP) 2015-11-10 US disclosed
US-20150141401-A1 NOVEL BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME MEIJI SEIKA PHARMA CO., LTD. (JP) 2015-05-21 US disclosed
EP-2857401-A1 NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME Meiji Seika Pharma Co., Ltd. (JP) 2015-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731971-B2 Processes for preparing a diazabicyclooctane compound FN1, BMP1, AZI2 FKBP1A 2462/4885ALDH1A1 1362/4885TSHR 1888/4885
US-20220348578-A1 CRYSTALLINE FORMS OF DIAZABICYCLOOCTANE DERIVATIVE AND PRODUCTION PROCESS THEREOF CCNA1, RCC1, DDT FKBP1A 2118/4885ALDH1A1 1981/4885TSHR 3422/4885
US-20250059191-A1 CRYSTALLINE FORMS OF DIAZABICYCLOOCTANE DERIVATIVE AND PRODUCTION PROCESS THEREOF CCNA1, RCC1, DDT FKBP1A 2118/4885ALDH1A1 1981/4885TSHR 3422/4885
US-20160272641-A1 CRYSTALLINE FORMS OF DIAZABICYCLOOCTANE DERIVATIVE AND PRODUCTION PROCESS THEREOF DDT, CYP51A1, ODC1 FKBP1A 780/4885ALDH1A1 2440/4885TSHR 2883/4885
US-20160024090-A1 BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME ME1, MRPL21, FNTB FKBP1A 2852/4885ALDH1A1 502/4885TSHR 1913/4885
US-12221443-B2 Crystalline forms of diazabicyclooctane derivative and production process thereof CCNA1, RCC1, DDT FKBP1A 2118/4885ALDH1A1 1981/4885TSHR 3422/4885
US-20150141401-A1 NOVEL BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME ME1, FN1, FNTB FKBP1A 3178/4885ALDH1A1 466/4885TSHR 1719/4885
US-20210371419-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND FN1, BMP1, AZI2 FKBP1A 2462/4885ALDH1A1 1362/4885TSHR 1888/4885
US-20180258089-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND FN1, BMP1, AZI2 FKBP1A 2462/4885ALDH1A1 1362/4885TSHR 1888/4885
US-10023573-B2 Beta-lactamase inhibitor and process for preparing the same FN1, FNTB, CPN1 FKBP1A 2969/4885ALDH1A1 495/4885TSHR 3303/4885
US-11414417-B2 Crystalline forms of diazabicyclooctane derivative and production process thereof CCNA1, RCC1, DDT FKBP1A 2118/4885ALDH1A1 1981/4885TSHR 3422/4885
US-10131665-B2 Processes for producing diazabicyclooctane compounds DDT, ODC1, CYP51A1 FKBP1A 1399/4885ALDH1A1 1514/4885TSHR 3629/4885
US-20230331724-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND FN1, BMP1, AZI2 FKBP1A 2462/4885ALDH1A1 1362/4885TSHR 1888/4885
US-12103928-B2 Processes for preparing a diazabicyclooctane compound FN1, BMP1, AZI2 FKBP1A 2462/4885ALDH1A1 1362/4885TSHR 1888/4885
US-20170233393-A1 BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME FN1, FNTB, CPN1 FKBP1A 2969/4885ALDH1A1 495/4885TSHR 3303/4885
US-11117896-B2 Processes for preparing a diazabicyclooctane compound FN1, BMP1, AZI2 FKBP1A 2462/4885ALDH1A1 1362/4885TSHR 1888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.