Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 5/20 | 0.47 |
| ▸ | RARB | P10826 | 5/20 | 0.47 |
| ▸ | RARG | P13631 | 4/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12620996 | 0.92 | RARA (0.45) | RARARARBRARGRXRAFAAH | |
| SCHEMBL12620979 | 0.87 | ENPP2 (0.43) | RARARARBRARGRXRAFAAH | |
| SCHEMBL12620974 | 0.87 | HSD11B1 (0.45) | RARARARBRARGALDH1A1SMN1; SMN2 | |
| SCHEMBL13807569 | 0.86 | GPR119 (0.47) | FAAHALDH1A1 | |
| SCHEMBL12620840 | 0.85 | ALDH1A1 (0.46) | RARARARBRARGRXRAALDH1A1 | |
| SCHEMBL2222685 | 0.85 | RARA (0.40) | RARARARBRARGRXRAFAAH | |
| SCHEMBL12620986 | 0.85 | RARB (0.40) | RARARARBRARGRXRAFAAH | |
| SCHEMBL12621000 | 0.85 | CTSL (0.40) | RARARARBRARGRXRAFAAH | |
| SCHEMBL12621009 | 0.85 | CTSL (0.40) | RARARARBRARGRXRAFAAH | |
| SCHEMBL12620952 | 0.85 | HSD11B1 (0.43) | RARARARBFAAHALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313403-B1 | THIAZOLYL PIPERDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-04-08 | — | — | EP | claimed |