Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249950 | 0.87 | ALDH1A1 (0.51) | ALDH1A1HSD17B10MAPK1RAB9ACYP1A2 | |
| SCHEMBL16619524 | 0.75 | ATAD2 (0.46) | CYP3A4FFAR1HDAC1 | |
| SCHEMBL16619017 | 0.74 | AKR1C3 (0.47) | ALDH1A1RAB9ACYP1A2FFAR1 | |
| SCHEMBL8426541 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MAPK1RAB9ACYP1A2 | |
| SCHEMBL16619801 | 0.73 | ALDH1A1 (0.55) | ALDH1A1HSD17B10MAPK1RAB9ACYP1A2 | |
| SCHEMBL20032548 | 0.68 | ALDH1A1 (0.64) | ALDH1A1HSD17B10MAPK1RAB9ACYP1A2 | |
| SCHEMBL374339 | 0.68 | ALDH1A1 (0.67) | ALDH1A1HSD17B10MAPK1RAB9ACYP1A2 | |
| SCHEMBL12095422 | 0.68 | FFAR1 (0.44) | HSD17B10FFAR1HDAC1METAXL | |
| SCHEMBL16619466 | 0.68 | BRD4 (0.48) | CYP3A4METAXL | |
| SCHEMBL15057556 | 0.67 | ALDH1A1 (0.54) | ALDH1A1HSD17B10MAPK1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |