Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.45 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 8/20 | 0.42 |
| ▸ | THRB | P10828 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16621894 | 0.83 | NPSR1 (0.50) | POLBIMPDH2NPSR1THRATHRB | |
| SCHEMBL27747620 | 0.72 | MEN1 (0.47) | POLBIMPDH2NPSR1THRATHRB | |
| SCHEMBL9037504 | 0.72 | POLB (0.65) | POLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL7820588 | 0.71 | SMN1; SMN2 (0.58) | POLBNPSR1CA1CA2 | |
| SCHEMBL21317652 | 0.71 | POLB (0.59) | POLBNPSR1ALDH1A1 | |
| SCHEMBL3688663 | 0.71 | TRPV1 (0.52) | POLBNPSR1ALDH1A1CA1CA2 | |
| SCHEMBL7952084 | 0.71 | THRA (0.58) | THRATHRBHSD17B10 | |
| SCHEMBL728842 | 0.70 | CA2 (0.58) | TPMTALDH1A1HPGDGPR35HSD17B10 | |
| SCHEMBL21317651 | 0.70 | POLB (0.58) | POLBNPSR1ALDH1A1 | |
| SCHEMBL16293919 | 0.70 | POLB (0.47) | POLBIMPDH2NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000216-B2 | Iodoarene derivative, method for manufacturing optically active spirolactone compound by using the same, and method for manufacturing optically active cycloadduct | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-04-07 | — | — | US | disclosed |