SCHEMBL3849043

SCHEMBL3849043

Clc1ccnc(-c2cccc(-c3ccccc3)c2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.53
ASIC3 Q9UHC3 2/20 0.47
CNR1 P21554 1/20 0.47
KMO O15229 4/20 0.46
CCR1 P32246 1/20 0.43
CCR5 P51681 1/20 0.43
CCR8 P51685 1/20 0.43
IDO1 P14902 1/20 0.42
SMO Q99835 2/20 0.42
PLK1 P53350 1/20 0.41
NPC1 O15118 1/20 0.41
MITF O75030 1/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
TSHR P16473 1/20 0.41
GRM5 P41594 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAP4K4 O95819 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1662224 0.88 ASIC3 (0.59) PIM1ASIC3CNR1KMOCCR1
SCHEMBL15947898 0.86 PIM1 (0.57) PIM1KMOIDO1PLK1NPC1
SCHEMBL31074875 0.86 PIM1 (0.48) PIM1ASIC3CNR1KMOCCR1
Hydrochloric Acid SCHEMBL15659071 0.85 PIM1 (0.55) PIM1KMOIDO1PLK1NPC1
SCHEMBL28116354 0.84 ASIC3 (0.53) PIM1ASIC3KMOSMO
SCHEMBL12408985 0.84 ASIC3 (0.53) PIM1ASIC3KMOSMO
SCHEMBL25633157 0.82 ASIC3 (0.52) PIM1ASIC3KMOSMOMAP4K4
SCHEMBL25492416 0.80 KMO (0.49) PIM1KMOIDO1MAPTGRM5
SCHEMBL9792755 0.80 MAPT (0.46) PIM1KMOIDO1PLK1NPC1
SCHEMBL13875053 0.78 ASIC3 (0.47) PIM1ASIC3CNR1KMOGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9899612-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-20 US disclosed
US-9899612-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-20 US disclosed
US-9899612-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-20 US disclosed
US-20140284585-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2014-09-25 US disclosed
US-20140284585-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2014-09-25 US disclosed
US-20140284585-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2014-09-25 US disclosed
US-8778508-B2 Light-emitting organometallic complexes UNIVERSAL DISPLAY CORPORATION (US) 2014-07-15 US disclosed
US-8778508-B2 Light-emitting organometallic complexes UNIVERSAL DISPLAY CORPORATION (US) 2014-07-15 US disclosed
US-8778508-B2 Light-emitting organometallic complexes UNIVERSAL DISPLAY CORPORATION (US) 2014-07-15 US disclosed
US-8519130-B2 Method for synthesis of iriduim (III) complexes with sterically demanding ligands UNIVERSAL DISPLAY CORPORATION (US) 2013-08-27 US disclosed
WO-2009073246-A1 METHOD FOR THE SYNTHESIS OF IRIDIUM (III) COMPLEXES WITH STERICALLY DEMANDING LIGANDS UNIVERSAL DISPLAY CORPORATION (US) 2009-06-11 WO disclosed
WO-2009073245-A1 LIGHT-EMITTING ORGANOMETALLIC COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2009-06-11 WO disclosed
WO-2009073246-A1 METHOD FOR THE SYNTHESIS OF IRIDIUM (III) COMPLEXES WITH STERICALLY DEMANDING LIGANDS UNIVERSAL DISPLAY CORPORATION (US) 2009-06-11 WO disclosed
WO-2009073245-A1 LIGHT-EMITTING ORGANOMETALLIC COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2009-06-11 WO disclosed
US-20090124805-A1 METHOD FOR SYNTHESIS OF IRIDUIM (III) COMPLEXES WITH STERICALLY DEMANDING LIGANDS UNIVERSAL DISPLAY CORPORATION 2009-05-14 US disclosed
US-20090124805-A1 METHOD FOR SYNTHESIS OF IRIDUIM (III) COMPLEXES WITH STERICALLY DEMANDING LIGANDS UNIVERSAL DISPLAY CORPORATION 2009-05-14 US disclosed
US-20090124805-A1 METHOD FOR SYNTHESIS OF IRIDUIM (III) COMPLEXES WITH STERICALLY DEMANDING LIGANDS UNIVERSAL DISPLAY CORPORATION 2009-05-14 US disclosed
US-20090108737-A1 LIGHT-EMITTING ORGANOMETALLIC COMPLEXES UNIVERSAL DISPLAY CORPORATION 2009-04-30 US disclosed
US-20090108737-A1 LIGHT-EMITTING ORGANOMETALLIC COMPLEXES UNIVERSAL DISPLAY CORPORATION 2009-04-30 US disclosed
US-20090108737-A1 LIGHT-EMITTING ORGANOMETALLIC COMPLEXES UNIVERSAL DISPLAY CORPORATION 2009-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090108737-A1 LIGHT-EMITTING ORGANOMETALLIC COMPLEXES CRY1, LAGE3, CRY2 PIM1 212/4885ASIC3 1022/4885CNR1 4772/4885
US-20090124805-A1 METHOD FOR SYNTHESIS OF IRIDUIM (III) COMPLEXES WITH STERICALLY DEMANDING LIGANDS PAICS, ITPA, MPI PIM1 320/4885ASIC3 1263/4885CNR1 3907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.