Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16623507 | 0.84 | ITGA4 (0.33) | PTGS2 | |
| SCHEMBL17849242 | 0.81 | PTGS2 (0.34) | PTGS2PARP1 | |
| SCHEMBL16623600 | 0.72 | TYK2 (0.34) | PARP1 | |
| SCHEMBL17849229 | 0.69 | F10 (0.35) | PTGS2 | |
| SCHEMBL16726656 | 0.68 | PTGS2 (0.33) | PTGS2PARP1 | |
| SCHEMBL16623601 | 0.66 | PRSS1 (0.37) | PTGS2 | |
| SCHEMBL16623562 | 0.65 | LOXL2 (0.39) | — | |
| SCHEMBL16623485 | 0.65 | PARP1 (0.37) | PARP1 | |
| SCHEMBL16726648 | 0.65 | KDR (0.33) | PARP1 | |
| SCHEMBL16623511 | 0.64 | TYK2 (0.38) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857400-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |