Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 2/20 | 0.37 |
| ▸ | ADH1C | P00326 | 2/20 | 0.37 |
| ▸ | ADH1A | P07327 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | CPA1 | P15085 | 2/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16623913 | 1.00 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1ADH1BADH1CADH1A | |
| SCHEMBL16623919 | 1.00 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1ADH1BADH1CADH1A | |
| SCHEMBL18098723 | 1.00 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1ADH1BADH1CADH1A | |
| SCHEMBL16623912 | 1.00 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1ADH1BADH1CADH1A | |
| SCHEMBL2377589 | 0.83 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1ADH1BADH1CADH1A | |
| SCHEMBL2377592 | 0.83 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1ADH1BADH1CADH1A | |
| SCHEMBL9825702 | 0.83 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1ADH1BADH1CADH1A | |
| SCHEMBL28671686 | 0.82 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1ADH1BADH1CADH1A | |
| SCHEMBL8020557 | 0.82 | ENPEP (0.39) | ALDH1A1L3MBTL1ADH1BADH1CADH1A | |
| SCHEMBL28664873 | 0.82 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099800-A1 | NOVEL LIPASE INHIBITORS, REPORTER SUBSTRATES AND USES THEREOF | NIH - DEITR | 2015-04-09 | — | — | US | disclosed |
| US-20150099800-A1 | NOVEL LIPASE INHIBITORS, REPORTER SUBSTRATES AND USES THEREOF | NIH - DEITR | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099800-A1 | NOVEL LIPASE INHIBITORS, REPORTER SUBSTRATES AND USES THEREOF | PNLIP, LIPE, LIPC | ALDH1A1 2721/4885L3MBTL1 208/4885ADH1B 2336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.