Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16623960 | 0.75 | GAA (0.34) | GAAL3MBTL1KDM4EALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL5429867 | 0.74 | GAA (0.36) | GAAL3MBTL1KDM4EALDH1A1ALOX15 | |
| SCHEMBL16626770 | 0.68 | ALDH1A1 (0.40) | GAAL3MBTL1KDM4EALDH1A1ALOX15 | |
| SCHEMBL7510697 | 0.68 | GAA (0.44) | GAAL3MBTL1KDM4EALDH1A1ALOX15 | |
| SCHEMBL7508932 | 0.68 | GAA (0.47) | GAAL3MBTL1KDM4EALDH1A1ALOX15 | |
| SCHEMBL2769180 | 0.67 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL172020 | 0.67 | CES2 (0.32) | ALDH1A1 | |
| SCHEMBL7073928 | 0.67 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL16626765 | 0.67 | ALDH1A1 (0.49) | GAAL3MBTL1KDM4EALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL8777405 | 0.67 | GAA (0.47) | GAAL3MBTL1KDM4EALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10780026-B2 | Methods of forming dental composites and compositions for reduced shrinkage stress | DENTSPLY SIRONA INC. (US) | 2020-09-22 | — | — | US | disclosed |
| EP-3052481-B1 | USE OF POLYMERIZABLE STABLE RADICALS FOR REDUCING THE SHRINKAGE STRESS OF DENTAL COMPOSITIONS | DENTSPLY SIRONA INC (US) | 2020-04-08 | — | — | EP | disclosed |
| US-20190224081-A1 | METHODS OF FORMING DENTAL COMPOSITES AND COMPOSITIONS FOR REDUCED SHRINKAGE STRESS | DENTSPLY SIRONA INC (US) | 2019-07-25 | — | — | US | disclosed |
| US-9931280-B2 | Dental composite compositions for reduced shrinkage stress | DENTSPLY SIRONA INC. (US) | 2018-04-03 | — | — | US | disclosed |
| WO-2015051217-A1 | DENTAL COMPOSITE COMPOSITIONS FOR REDUCED STRESS SHRINKAGE | DENTSPLY INTERNATIONAL INC. (US) | 2015-04-09 | — | — | WO | disclosed |
| US-20150099821-A1 | DENTAL COMPOSITE COMPOSITIONS FOR REDUCED STRESS SHRINKAGE | DENTSPLY SIRONA INC. | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099821-A1 | DENTAL COMPOSITE COMPOSITIONS FOR REDUCED STRESS SHRINKAGE | VCL, HSPA4L, GPX4 | GAA 3472/4885L3MBTL1 1689/4885KDM4E 998/4885 |
| US-10780026-B2 | Methods of forming dental composites and compositions for reduced shrinkage stress | SMCHD1, FHIT, ACR | GAA 2587/4885L3MBTL1 4161/4885KDM4E 1577/4885 |
| US-20190224081-A1 | METHODS OF FORMING DENTAL COMPOSITES AND COMPOSITIONS FOR REDUCED SHRINKAGE STRESS | SMCHD1, FHIT, ACR | GAA 2587/4885L3MBTL1 4161/4885KDM4E 1577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.