Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26325075 | 0.95 | ALDH1A1 (0.48) | ALDH1A1GAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL16621434 | 0.87 | GAA (0.51) | ALDH1A1GAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL15497463 | 0.85 | RAB9A (0.65) | ALDH1A1GAAMEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9526742 | 0.78 | ALDH1A1 (0.47) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL9255856 | 0.75 | ALDH1A1 (0.53) | ALDH1A1GAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL129762 | 0.75 | ACHE (0.57) | ALDH1A1MEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL10030804 | 0.75 | ACHE (0.43) | ALDH1A1KDM4ETDP1MAPTMAPK1 | |
| SCHEMBL8400954 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TDP1ACHETSHRTAS1R3 | |
| SCHEMBL1155340 | 0.74 | MEN1 (0.48) | ALDH1A1GAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL8382704 | 0.73 | ALDH1A1 (0.66) | ALDH1A1GAAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
| WO-2018213572-A9 | PREPARATION OF SECONDARY AMINES WITH ELECTROPHILIC N-LINCHPIN REAGENTS | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-12-13 | — | — | WO | disclosed |
| WO-2018213572-A1 | PREPARATION OF SECONDARY AMINES WITH ELECTROPHILIC N-LINCHPIN REAGENTS | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-11-22 | — | — | WO | disclosed |
| US-9997714-B2 | Hole transport material | MERCK PATENT GMBH (DE) | 2018-06-12 | — | — | US | disclosed |
| US-9997714-B2 | Hole transport material | MERCK PATENT GMBH (DE) | 2018-06-12 | — | — | US | disclosed |
| US-20160254449-A1 | HOLE TRANSPORT MATERIAL | MERCK PATENT GMBH (DE) | 2016-09-01 | — | — | US | disclosed |
| US-20160254449-A1 | HOLE TRANSPORT MATERIAL | MERCK PATENT GMBH (DE) | 2016-09-01 | — | — | US | disclosed |
| WO-2015049031-A1 | HOLE TRANSPORT MATERIAL | MERCK PATENT GMBH (DE) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | ALDH1A1 1805/4885GAA 3549/4885MEN1 296/4885 |
| US-20160254449-A1 | HOLE TRANSPORT MATERIAL | SUN2, SLC6A19, SLCO2A1 | ALDH1A1 3172/4885GAA 4349/4885MEN1 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.