Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19424008 | 0.85 | ALDH1A1 (0.45) | ALDH1A1ALOX15GAAKDM4EHTT | |
| SCHEMBL16626767 | 0.84 | ALDH1A1 (0.49) | ALDH1A1ALOX15GAAL3MBTL1KDM4E | |
| SCHEMBL19424049 | 0.81 | — | — | |
| SCHEMBL19424062 | 0.78 | ALDH1A1 (0.39) | ALDH1A1ALOX15GAAKDM4E | |
| SCHEMBL16626770 | 0.75 | ALDH1A1 (0.40) | ALDH1A1ALOX15GAAL3MBTL1KDM4E | |
| SCHEMBL22722078 | 0.74 | ALDH1A1 (0.39) | ALDH1A1ALOX15GAAKDM4E | |
| SCHEMBL13074752 | 0.70 | ALDH1A1 (0.42) | ALDH1A1ALOX15GAAL3MBTL1KDM4E | |
| SCHEMBL5072323 | 0.70 | CYP2C9 (0.38) | ALDH1A1ALOX15 | |
| SCHEMBL21163316 | 0.69 | GAA (0.46) | ALDH1A1ALOX15GAAL3MBTL1KDM4E | |
| SCHEMBL7073396 | 0.69 | GAA (0.35) | ALDH1A1ALOX15GAAL3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436527-B1 | CROSSLINKABLE POLYMERIC COMPOSITIONS WITH METHYL-RADICAL SCAVENGERS AND ARTICLES MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-09-06 | — | — | EP | disclosed |
| US-10851221-B2 | Crosslinkable polymeric compositions with methyl-radical scavengers and articles made therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-12-01 | — | — | US | disclosed |
| US-20200299483-A1 | Crosslinkable Polymeric Compositions with Methyl-Radical Scavengers and Articles Made Therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2020-09-24 | — | — | US | disclosed |
| US-10780026-B2 | Methods of forming dental composites and compositions for reduced shrinkage stress | DENTSPLY SIRONA INC. (US) | 2020-09-22 | — | — | US | disclosed |
| US-20190224081-A1 | METHODS OF FORMING DENTAL COMPOSITES AND COMPOSITIONS FOR REDUCED SHRINKAGE STRESS | DENTSPLY SIRONA INC (US) | 2019-07-25 | — | — | US | disclosed |
| US-9931280-B2 | Dental composite compositions for reduced shrinkage stress | DENTSPLY SIRONA INC. (US) | 2018-04-03 | — | — | US | disclosed |
| WO-2017166762-A1 | CROSSLINKABLE POLYMERIC COMPOSITIONS WITH METHYL-RADICAL SCAVENGERS AND ARTICLES MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-10-05 | — | — | WO | disclosed |
| US-20150099821-A1 | DENTAL COMPOSITE COMPOSITIONS FOR REDUCED STRESS SHRINKAGE | DENTSPLY SIRONA INC. | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099821-A1 | DENTAL COMPOSITE COMPOSITIONS FOR REDUCED STRESS SHRINKAGE | VCL, HSPA4L, GPX4 | ALDH1A1 2471/4885ALOX15 598/4885GAA 3472/4885 |
| US-10780026-B2 | Methods of forming dental composites and compositions for reduced shrinkage stress | SMCHD1, FHIT, ACR | ALDH1A1 1551/4885ALOX15 387/4885GAA 2587/4885 |
| US-20190224081-A1 | METHODS OF FORMING DENTAL COMPOSITES AND COMPOSITIONS FOR REDUCED SHRINKAGE STRESS | SMCHD1, FHIT, ACR | ALDH1A1 1551/4885ALOX15 387/4885GAA 2587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.