Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626085 | 0.86 | ROCK2 (0.36) | GRM5GRIN2BGRIN1RXRAWNK1 | |
| SCHEMBL19983774 | 0.86 | BACE1 (0.34) | GRIN2BGRIN1CFDRXRARORC | |
| SCHEMBL16626086 | 0.83 | GRIN2B (0.38) | GRM5GRIN2BGRIN1METAP2PIK3CB | |
| SCHEMBL17971574 | 0.79 | RORC (0.49) | GRM5GRIN2BGRIN1METAP2CFD | |
| Hydrochloric Acid SCHEMBL16618537 | 0.79 | RORC (0.48) | GRM5GRIN2BGRIN1METAP2CFD | |
| SCHEMBL16626643 | 0.76 | BACE1 (0.35) | GRIN2BGRIN1 | |
| SCHEMBL16626590 | 0.70 | L3MBTL1 (0.33) | — | |
| SCHEMBL16626586 | 0.68 | EPHX2 (0.38) | METAP2 | |
| SCHEMBL19984032 | 0.66 | GRIN2B (0.39) | GRM5GRIN2BGRIN1METAP2PIK3CB | |
| SCHEMBL16626780 | 0.66 | RORC (0.48) | GRIN2BGRIN1RXRARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050412-A1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-04-09 | — | — | WO | disclosed |