Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627825 | 0.83 | KMT2A (0.53) | KDM4EALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL16627710 | 0.82 | KMT2A (0.52) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL16627828 | 0.79 | PARP14 (0.52) | KDM4EALDH1A1KMT2AMEN1NLRP3 | |
| SCHEMBL16627690 | 0.76 | RXFP1 (0.40) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL16627593 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL16627727 | 0.73 | HTT (0.44) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL16627729 | 0.73 | HTT (0.48) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL16627869 | 0.71 | ALDH1A1 (0.43) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL16627678 | 0.71 | PARP14 (0.52) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL16627890 | 0.70 | PARP14 (0.56) | KDM4EALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |