Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627825 | 0.90 | KMT2A (0.53) | KMT2APARP14MAPTLMNATP53 | |
| SCHEMBL16627592 | 0.82 | MT-CO2 (0.44) | KMT2APARP14ALDH1A1KDM4EMEN1 | |
| SCHEMBL16627760 | 0.79 | CCNA2 (0.45) | KMT2APARP14POLBRXFP1TDP1 | |
| SCHEMBL16627828 | 0.79 | PARP14 (0.52) | KMT2APARP14MAPTLMNATP53 | |
| SCHEMBL16627678 | 0.79 | PARP14 (0.52) | KMT2APARP14MAPTLMNATP53 | |
| SCHEMBL16627869 | 0.75 | ALDH1A1 (0.43) | KMT2AMAPTTDP1ALDH1A1KDM4E | |
| SCHEMBL16627729 | 0.71 | HTT (0.48) | KMT2AMAPTLMNATP53POLB | |
| SCHEMBL16627727 | 0.71 | HTT (0.44) | KMT2AMAPTLMNAPOLBRXFP1 | |
| SCHEMBL16627890 | 0.69 | PARP14 (0.56) | KMT2APARP14MAPTLMNAPOLB | |
| SCHEMBL16627806 | 0.69 | NHERF1 (0.49) | KMT2AMAPTTP53POLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |