Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627727 | 0.86 | HTT (0.44) | HTTNPC1RAB9AKDM4EGAA | |
| SCHEMBL16627739 | 0.78 | SMYD3 (0.50) | HTTNPC1RAB9AKDM4EGAA | |
| SCHEMBL16627869 | 0.75 | ALDH1A1 (0.43) | HTTNPC1RAB9AKDM4EGAA | |
| SCHEMBL16627825 | 0.74 | KMT2A (0.53) | HTTNPC1RAB9AKDM4EGAA | |
| SCHEMBL16627592 | 0.73 | MT-CO2 (0.44) | HTTNPC1RAB9AKDM4EGAA | |
| SCHEMBL16627710 | 0.71 | KMT2A (0.52) | HTTNPC1RAB9AKDM4EGAA | |
| SCHEMBL16627616 | 0.69 | PARP1 (0.53) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL16627868 | 0.69 | KDM4E (0.48) | HTTNPC1KDM4EGAAABCG2 | |
| SCHEMBL16627831 | 0.69 | KDM4E (0.51) | NPC1RAB9AKDM4EGAAKMT2A | |
| SCHEMBL16627890 | 0.69 | PARP14 (0.56) | NPC1RAB9AKDM4EABCG2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |