Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | DDO | Q99489 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PYGM | P11217 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | IL4I1 | Q96RQ9 | 3/20 | 0.39 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627633 | 0.86 | BRD4 (0.46) | DAODDOBRD4KDM4EALDH1A1 | |
| SCHEMBL16627647 | 0.84 | DAO (0.54) | DAODDOBRD4KDM4EALDH1A1 | |
| SCHEMBL16627639 | 0.84 | PYGM (0.55) | DAODDOBRD4KDM4EALDH1A1 | |
| SCHEMBL16627659 | 0.81 | BRD4 (0.58) | DAODDOBRD4KDM4EALDH1A1 | |
| SCHEMBL16627640 | 0.80 | BRD4 (0.45) | DAODDOBRD4KDM4EALDH1A1 | |
| SCHEMBL16627732 | 0.79 | DAO (0.55) | DAODDOBRD4KDM4EALDH1A1 | |
| SCHEMBL16627631 | 0.78 | BRD4 (0.43) | DAODDOBRD4KDM4EALDH1A1 | |
| SCHEMBL16627660 | 0.77 | HPGD (0.50) | BRD4KDM4EGAAMAPTHPGD | |
| SCHEMBL16627731 | 0.76 | BRD4 (0.55) | DAODDOBRD4KDM4EALDH1A1 | |
| SCHEMBL12909532 | 0.71 | BRD4 (0.59) | DAODDOBRD4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |