Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | DDO | Q99489 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627659 | 0.85 | BRD4 (0.58) | BRD4KMT2AMEN1MAPTRAB9A | |
| SCHEMBL16627639 | 0.82 | PYGM (0.55) | BRD4KMT2AMEN1MAPTRAB9A | |
| SCHEMBL16627732 | 0.80 | DAO (0.55) | BRD4KMT2AMEN1MAPTRAB9A | |
| SCHEMBL16627647 | 0.79 | DAO (0.54) | BRD4KMT2AMEN1MAPTRAB9A | |
| SCHEMBL16627633 | 0.79 | BRD4 (0.46) | BRD4KMT2AMEN1MAPTRAB9A | |
| SCHEMBL16627640 | 0.78 | BRD4 (0.45) | BRD4KMT2AMEN1MAPTRAB9A | |
| SCHEMBL16627634 | 0.76 | DAO (0.46) | BRD4MAPTSMN1; SMN2DAODDO | |
| SCHEMBL16627631 | 0.76 | BRD4 (0.43) | BRD4KMT2AMEN1MAPTDAO | |
| SCHEMBL34468855 | 0.76 | KMT2A (0.62) | BRD4KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL16627660 | 0.75 | HPGD (0.50) | BRD4KMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |