Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | CDC25B | P30305 | 1/20 | 0.54 |
| ▸ | UBE2I | P63279 | 1/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.54 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | DDO | Q99489 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627639 | 0.87 | PYGM (0.55) | BRD4CDC25BUBE2ISAE1UBA2 | |
| SCHEMBL16627731 | 0.85 | BRD4 (0.55) | BRD4CDC25BUBE2ISAE1UBA2 | |
| SCHEMBL16627647 | 0.85 | DAO (0.54) | BRD4MMP2MMP9MMP8MMP13 | |
| SCHEMBL16627633 | 0.84 | BRD4 (0.46) | BRD4RAB9ANPC1DAODDO | |
| SCHEMBL16627640 | 0.84 | BRD4 (0.45) | BRD4CDC25BUBE2ISAE1UBA2 | |
| SCHEMBL16627631 | 0.81 | BRD4 (0.43) | BRD4CDC25BUBE2ISAE1UBA2 | |
| SCHEMBL16627634 | 0.81 | DAO (0.46) | BRD4MMP2MMP9MMP8MMP13 | |
| SCHEMBL16627660 | 0.80 | HPGD (0.50) | BRD4NPC1KDM4EMEN1KMT2A | |
| SCHEMBL16627732 | 0.79 | DAO (0.55) | BRD4CDC25BRAB9ANPC1DAO | |
| SCHEMBL12909532 | 0.77 | BRD4 (0.59) | BRD4DAODDOKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |