Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | DDO | Q99489 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | PYGM | P11217 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627639 | 0.86 | PYGM (0.55) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL16627647 | 0.84 | DAO (0.54) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL16627659 | 0.84 | BRD4 (0.58) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL16627633 | 0.83 | BRD4 (0.46) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL16627631 | 0.80 | BRD4 (0.43) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL16627634 | 0.80 | DAO (0.46) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL16627660 | 0.79 | HPGD (0.50) | BRD4KDM4EMAPTGAAHPGD | |
| SCHEMBL16627731 | 0.78 | BRD4 (0.55) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL16627732 | 0.78 | DAO (0.55) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL12909532 | 0.73 | BRD4 (0.59) | BRD4DAODDOKDRCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |