Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | DDO | Q99489 | 1/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | ABL2 | P42684 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627639 | 0.87 | PYGM (0.55) | DAODDOPRKD3EGFRPRKCG | |
| SCHEMBL16627732 | 0.85 | DAO (0.55) | DAODDOBRD4CHEK1KDR | |
| SCHEMBL16627659 | 0.85 | BRD4 (0.58) | DAODDOEGFRBRD4CHEK1 | |
| SCHEMBL16627634 | 0.84 | DAO (0.46) | DAODDOBRD4CHEK1KDR | |
| SCHEMBL16627640 | 0.84 | BRD4 (0.45) | DAODDOBRD4CHEK1KDR | |
| SCHEMBL16627631 | 0.81 | BRD4 (0.43) | DAODDOBRD4CHEK1KDR | |
| SCHEMBL16627633 | 0.81 | BRD4 (0.46) | DAODDOBRD4CHEK1KDR | |
| SCHEMBL16627660 | 0.80 | HPGD (0.50) | BRD4GAAMAPTKDM4EMAPK1 | |
| SCHEMBL16627731 | 0.79 | BRD4 (0.55) | DAODDOBRD4CHEK1KDR | |
| SCHEMBL486475 | 0.75 | MAOB (0.56) | DAODDOEGFRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |