Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627639 | 0.82 | PYGM (0.55) | HPGDKMT2AMEN1NPC1MAPT | |
| SCHEMBL7694809 | 0.82 | HPGD (0.54) | HPGDALOX12L3MBTL1CXCR2KMT2A | |
| SCHEMBL16627647 | 0.80 | DAO (0.54) | HPGDKMT2AMEN1NPC1MAPT | |
| SCHEMBL16627659 | 0.80 | BRD4 (0.58) | HPGDKMT2APOLBMEN1NPC1 | |
| SCHEMBL16627640 | 0.79 | BRD4 (0.45) | HPGDKMT2AMEN1NPC1MAPT | |
| SCHEMBL16627822 | 0.77 | MAPT (0.58) | L3MBTL1KMT2APOLBMEN1NPC1 | |
| SCHEMBL16627631 | 0.77 | BRD4 (0.43) | HPGDKMT2AMEN1MAPTGAA | |
| SCHEMBL16627633 | 0.77 | BRD4 (0.46) | HPGDKMT2AMEN1NPC1MAPT | |
| SCHEMBL16627634 | 0.77 | DAO (0.46) | HPGDMAPTGAAKDM4EMAPK1 | |
| SCHEMBL8987068 | 0.76 | KDR (0.54) | GRIA1GRIA2GRIA3GRIA4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |