Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA7 | P43166 | 5/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673906 | 0.86 | ITGB3 (0.41) | CA1CA2CA12CA7CA14 | |
| SCHEMBL25081053 | 0.81 | AADAT (0.41) | CA1CA2CA12CA7CA14 | |
| SCHEMBL6641852 | 0.80 | ALDH1A1 (0.46) | CA1CA2CA12CA7CA14 | |
| SCHEMBL2330713 | 0.80 | IDO1 (0.44) | MAPTHSD17B10CYP19A1 | |
| SCHEMBL30595345 | 0.80 | IDO1 (0.44) | MAPTHSD17B10CYP19A1 | |
| SCHEMBL6641688 | 0.79 | NPC1 (0.49) | CA1CA2CA12CA7CA14 | |
| SCHEMBL27468308 | 0.77 | BRD4 (0.42) | CA1CA2CA12CA7CA14 | |
| SCHEMBL7316308 | 0.74 | ITGB3 (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7796017 | 0.74 | DGAT1 (0.55) | BRD4ATAD2MAPTMCHR1ITGB3 | |
| SCHEMBL22102109 | 0.74 | ALDH1A1 (0.37) | CA1CA2CA12CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |