Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437134 | 0.84 | GAA (0.56) | EPHX2PPARGALDH1A1MEN1LMNA | |
| SCHEMBL21900500 | 0.83 | ALDH1A1 (0.46) | EPHX2PPARGALDH1A1MEN1LMNA | |
| SCHEMBL16621363 | 0.83 | ALDH1A1 (0.49) | EPHX2PPARGALDH1A1MEN1LMNA | |
| SCHEMBL16628135 | 0.81 | DHFR (0.46) | KCNA3EPHX2MEN1KMT2AP2RX7 | |
| SCHEMBL2387597 | 0.81 | PKM (0.53) | EPHX2PPARGALDH1A1MEN1KMT2A | |
| SCHEMBL16628144 | 0.80 | ALDH1A1 (0.43) | EPHX2PPARGALDH1A1MEN1LMNA | |
| SCHEMBL4071443 | 0.79 | ALDH1A1 (0.45) | EPHX2PPARGALDH1A1MEN1LMNA | |
| SCHEMBL13940054 | 0.79 | PPARG (0.44) | EPHX2PPARGALDH1A1MEN1LMNA | |
| SCHEMBL2748297 | 0.78 | MEN1 (0.51) | EPHX2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL7732958 | 0.77 | L3MBTL1 (0.57) | EPHX2PPARGALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051149-A1 | SORAFENIB ANALOGS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-04-09 | — | — | WO | disclosed |