Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043472 | 0.78 | NR3C1 (0.38) | JAK2JAK1 | |
| SCHEMBL16593218 | 0.78 | CHRM1 (0.53) | CHRM1 | |
| SCHEMBL22001367 | 0.70 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL16593249 | 0.67 | CHRM1 (0.50) | CHRM1 | |
| SCHEMBL19997556 | 0.66 | RPS6KB1 (0.42) | — | |
| SCHEMBL21042773 | 0.66 | CHRM1 (0.61) | CHRM1 | |
| SCHEMBL16593317 | 0.66 | CHRM1 (0.61) | CHRM1 | |
| SCHEMBL21042591 | 0.65 | P2RX3 (0.49) | CHRM1 | |
| SCHEMBL16593355 | 0.62 | CHRM1 (0.63) | CHRM1 | |
| SCHEMBL16593193 | 0.62 | CHRM1 (0.63) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049574-A1 | 4-AZAINDOLE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-09 | — | — | WO | disclosed |