Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001367 | 0.80 | SMN1; SMN2 (0.36) | POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL16628258 | 0.78 | CHRM1 (0.32) | JAK2JAK1 | |
| SCHEMBL16593218 | 0.78 | CHRM1 (0.53) | — | |
| SCHEMBL19997556 | 0.75 | RPS6KB1 (0.42) | POLBL3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL21042786 | 0.71 | POLB (0.47) | POLBL3MBTL1SMN1; SMN2FSCN1ALDH1A1 | |
| SCHEMBL21043087 | 0.69 | BRD4 (0.41) | NR3C1L3MBTL1ADRA1DJAK2JAK1 | |
| SCHEMBL16593249 | 0.69 | CHRM1 (0.50) | KCNH2 | |
| SCHEMBL22001757 | 0.67 | ALDH1A1 (0.33) | L3MBTL1SMN1; SMN2ALDH1A1MAPTKCNH2 | |
| SCHEMBL21043066 | 0.66 | POLB (0.69) | POLBL3MBTL1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL21043468 | 0.66 | CCR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-A1 | 4-AZAINDOLE DERIVATIVES | Eisai R&D Management Co., Ltd. (JP) | 2019-05-29 | — | — | EP | disclosed |