SCHEMBL16628532 — predicted protein targets

Known targets — ChEMBL curated mechanism

GABBR1 GABBR2 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRIN3A GRIN3B HMGCR MMP1 MMP13 MMP7 MMP8 PTGS1 PTGS2 ileS pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	PTGS1 known ✓	P23219	1/20	0.33

▸	CA1	P00915	17/20	0.52

▸	CA2	P00918	17/20	0.52

▸	CA12	O43570	16/20	0.52

▸	CA9	Q16790	16/20	0.52

▸	EHMT2	Q96KQ7	3/20	0.52

▸	EHMT1	Q9H9B1	3/20	0.52

▸	CA4	P22748	2/20	0.52

▸	ALDH1A1	P00352	2/20	0.45

▸	TP53	P04637	2/20	0.45

▸	HPGD	P15428	2/20	0.45

▸	ALOX15	P16050	2/20	0.45

▸	ALOX12	P18054	2/20	0.45

▸	HSD17B10	Q99714	2/20	0.45

▸	MAPK1	P28482	1/20	0.45

▸	HIF1A	Q16665	1/20	0.45

▸	TDP1	Q9NUW8	1/20	0.45

▸	ABCB11	O95342	2/20	0.33

▸	HTT	P42858	2/20	0.33

▸	GSDMD	P57764	2/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3898504	0.94	CA1 (0.52)	CA1CA2CA12CA9EHMT2
SCHEMBL27470251	0.94	CA1 (0.52)	CA1CA2CA12CA9EHMT2
SCHEMBL16628431	0.94	CA1 (0.52)	CA1CA2CA12CA9EHMT2
Potassium Ion SCHEMBL16628389	0.94	—	—
SCHEMBL10597250	0.94	CA1 (0.52)	CA1CA2CA12CA9EHMT2
SCHEMBL11492107	0.94	CA1 (0.52)	CA1CA2CA12CA9EHMT2
SCHEMBL10891745	0.94	—	—
SCHEMBL3691083	0.92	CA1 (0.50)	CA1CA2CA12CA9EHMT2
SCHEMBL5485538	0.89	CA12 (0.48)	CA1CA2CA12CA9EHMT2
SCHEMBL16628416	0.78	CA2 (0.59)	CA1CA2CA12CA9EHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2860170-B1	PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE	OSAKA ORGANIC CHEMICAL IND LTD (JP)	2019-08-28	—	—	EP	disclosed
US-9670129-B2	Process for preparing 4-hydroxybutyl acrylate	OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP)	2017-06-06	—	—	US	disclosed
US-20150126766-A1	PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE	OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP)	2015-05-07	—	—	US	disclosed
EP-2860170-A1	PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE	Osaka Organic Chemical Ind., Ltd. (JP)	2015-04-15	—	—	EP	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20150126766-A1	PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE	LTB4R2, LTA4H, LTB4R	PTGS1 151/4885CA1 4540/4885CA2 4547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.