Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.34 |
| ▸ | HTR3B | O95264 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1663063 | 0.99 | HTR7 (0.37) | HTR7FFAR4HTR2AHTR2CHTR6 | |
| Hydrochloric Acid SCHEMBL1583979 | 0.78 | HTR3E (0.45) | HTR7HTR2AHTR2CROCK2HTR3E | |
| Hydrochloric Acid SCHEMBL1665462 | 0.78 | SLC6A2 (0.47) | HTR2AHTR2CHTR6ROCK2KDR | |
| Hydrochloric Acid SCHEMBL1662924 | 0.77 | LMNA (0.38) | HTR2AHTR2CHTR6HTR3EHTR3B | |
| SCHEMBL2766363 | 0.76 | HTR3E (0.54) | HTR7FFAR4HTR6HTR3EHTR3B | |
| SCHEMBL8276483 | 0.75 | DRD2 (0.58) | HTR7HTR2AHTR2CHTR6HTR3E | |
| SCHEMBL1583742 | 0.75 | SLC6A2 (0.45) | HTR2CKDRKMT2A | |
| SCHEMBL1583680 | 0.75 | P2RX7 (0.42) | HTR2CKDRDRD2KMT2A | |
| Hydrochloric Acid SCHEMBL10705356 | 0.74 | ATM (0.59) | HTR7HTR2AHTR2CHTR6HTR3E | |
| SCHEMBL8306413 | 0.74 | HTR1A (0.39) | HTR7HTR2AHTR2CHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |