Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631928 | 0.84 | ADORA3 (0.31) | ADORA3 | |
| SCHEMBL18081943 | 0.80 | NSD2 (0.36) | NSD2CASP6HPGDSMN1; SMN2 | |
| SCHEMBL18080527 | 0.77 | SMN1; SMN2 (0.34) | NSD2CASP6HPGDSMN1; SMN2 | |
| SCHEMBL18081945 | 0.70 | LMNA (0.32) | NSD2CASP6HPGDSMN1; SMN2 | |
| SCHEMBL16631759 | 0.68 | KMT2A (0.32) | — | |
| SCHEMBL18080236 | 0.68 | PYGM (0.47) | HPGDHTT | |
| SCHEMBL16631887 | 0.67 | LMNA (0.46) | ADORA3SMN1; SMN2 | |
| SCHEMBL18080523 | 0.67 | LMNA (0.33) | SMN1; SMN2 | |
| SCHEMBL16631754 | 0.67 | MEN1 (0.33) | — | |
| SCHEMBL16631362 | 0.66 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |