Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 10/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28761010 | 0.84 | ACHE (0.59) | ACHEL3MBTL1POLBMAPTKDM4E | |
| SCHEMBL17924627 | 0.80 | ALDH1A1 (0.43) | L3MBTL1POLBMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL16632376 | 0.78 | ERN1 (0.39) | L3MBTL1POLBMAPTKDM4ENPC1 | |
| SCHEMBL30234246 | 0.78 | ERN1 (0.39) | L3MBTL1POLBMAPTKDM4ENPC1 | |
| SCHEMBL23648084 | 0.78 | ALDH1A1 (0.35) | ACHEMAPK1ALDH1A1MAOB | |
| SCHEMBL30833916 | 0.77 | ACHE (0.52) | ACHEL3MBTL1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL1126364 | 0.77 | ACHE (0.52) | ACHEL3MBTL1POLBMAPTKDM4E | |
| SCHEMBL30234361 | 0.77 | POLB (0.38) | L3MBTL1POLBMAPTNPSR1ALOX5 | |
| SCHEMBL9880773 | 0.76 | ACHE (0.70) | ACHEL3MBTL1MAPTKDM4ELMNA | |
| SCHEMBL3292936 | 0.74 | ALOX5 (0.67) | ACHEPOLBMAPTKDM4EALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170282170-A9 | PHOSPHORUS-CONTAINING CATALYSTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-10-05 | — | — | US | disclosed |
| US-20160207034-A1 | PHOSPHORUS-CONTAINING CATALYSTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-07-21 | — | — | US | disclosed |
| US-9382245-B2 | Compounds and methods for treating HIV infections | YALE UNIVERSITY (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150105351-A1 | COMPOUNDS AND METHODS FOR TREATING HIV INFECTIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207034-A1 | PHOSPHORUS-CONTAINING CATALYSTS | AR, NR2C2, ORC3 | ACHE 4007/4885L3MBTL1 3186/4885POLB 1228/4885 |
| US-20170282170-A9 | PHOSPHORUS-CONTAINING CATALYSTS | AR, NR2C2, ORC3 | ACHE 4007/4885L3MBTL1 3186/4885POLB 1228/4885 |
| US-20150105351-A1 | COMPOUNDS AND METHODS FOR TREATING HIV INFECTIONS | POLM, POLRMT, DHFR | ACHE 1975/4885L3MBTL1 879/4885POLB 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.