SCHEMBL16632631

SCHEMBL16632631

Cc1ccc(-n2c(-c3ccccc3)ncc(C(=O)OC3=CC(=O)CCC3)c2=O)cc1C

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.39
CA2 P00918 5/20 0.39
STAT1 P42224 1/20 0.39
MAPT P10636 5/20 0.36
NPSR1 Q6W5P4 1/20 0.36
POLB P06746 1/20 0.36
EEF2K O00418 1/20 0.35
KDM4E B2RXH2 2/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29575370 1.00 CA1 (0.39) CA1CA2STAT1MAPTNPSR1
SCHEMBL1527903 0.89 MAPT (0.37) MAPTKDM4ETSHRALDH1A1
SCHEMBL9895124 0.82 G6PD (0.41) MAPTPOLBALDH1A1
SCHEMBL9895322 0.80 MAPT (0.35) MAPTNPSR1KDM4EALDH1A1
SCHEMBL25208501 0.79 STAT1 (0.49) CA1CA2STAT1MAPTNPSR1
SCHEMBL9894267 0.77 ALDH1A1 (0.40) MAPTKDM4EALDH1A1
SCHEMBL1372778 0.69 MET (0.44)
SCHEMBL1527905 0.68 MAPT (0.58) STAT1MAPTPOLBKDM4ETSHR
SCHEMBL22289849 0.67 POLB (0.40) CA1CA2STAT1POLBKDM4E
SCHEMBL15570307 0.67 TP53 (0.44) MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098020-A1 HERBICIDAL PYRIMIDINYLMETHYL-SUBSTITUTED 1,2,4-TRIAZOLES FMC CORP (US) 2026-04-09 US disclosed
EP-4714942-A1 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC Corporation (US) 2026-03-25 EP disclosed
EP-4683908-A1 SUBSTITUTED OXAZOLIDINONES AND IMIDAZOLINONES AS HERBICIDES FMC Corporation (US) 2026-01-28 EP disclosed
EP-4188093-B9 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC CORP (US) 2025-12-03 EP disclosed
EP-3599868-B1 HERBICIDAL MIXTURE, COMPOSITION AND METHOD FMC CORP (US) 2025-09-24 EP disclosed
EP-4188093-B1 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC CORP (US) 2025-09-03 EP disclosed
WO-2025111184-A1 SUBSTITUTED TETRAHYDROQUINOLINE AND TETRAHYDROQUINOXALINE HERBICIDES FMC CORPORATION (US) 2025-05-30 WO disclosed
EP-4554941-A1 HERBICIDAL BENZOXAZINES FMC Corporation (US) 2025-05-21 EP disclosed
EP-4267556-B1 SUBSTITUTED PYRIDAZINONE HERBICIDES FMC CORP (US) 2025-04-09 EP disclosed
EP-4086240-B1 PYRROLIDINONE HERBICIDES FMC CORP (US) 2025-02-05 EP disclosed
US-20160297756-A1 PYRROLIDINONES AS HERBICIDES FMC CORPORATION 2016-10-13 US disclosed
EP-3073823-A1 STABILIZED LOW-CONCENTRATION METSULFURON-METHYL LIQUID COMPOSITION E. I. du Pont de Nemours and Company (US) 2016-10-05 EP disclosed
WO-2016149315-A1 SUBSTITUTED PYRIMIDINYLOXY PYRIDINE DERIVATIVES AS HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2016-09-22 WO disclosed
US-9302999-B2 Substituted triazoles as herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2016-04-05 US disclosed
US-20160068509-A1 PYRIDAZINONES AS HERBICIDES FMC CORPORATION 2016-03-10 US disclosed
WO-2016014814-A1 PYRIDONES AS HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2016-01-28 WO disclosed
WO-2015168010-A1 PYRIDAZINONE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2015-11-05 WO disclosed
US-20150284343-A1 SUBSTITUTED TRIAZOLES AS HERBICIDES FMC CORPORATION 2015-10-08 US disclosed
WO-2015077587-A1 STABILIZED LOW-CONCENTRATION METSULFURON-METHYL LIQUID COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2015-05-28 WO disclosed
US-20150105252-A1 SUBSTITUTED PYRAZOLES AS HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY 2015-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150284343-A1 SUBSTITUTED TRIAZOLES AS HERBICIDES CYP1B1, CYP1A1, CBR3 CA1 676/4885CA2 651/4885STAT1 1515/4885
US-20160297756-A1 PYRROLIDINONES AS HERBICIDES DDT, ARG1, PRMT1 CA1 1027/4885CA2 857/4885STAT1 2509/4885
US-20260098020-A1 HERBICIDAL PYRIMIDINYLMETHYL-SUBSTITUTED 1,2,4-TRIAZOLES CBR3, CBR1, CNPY3 CA1 748/4885CA2 82/4885STAT1 3980/4885
US-20160068509-A1 PYRIDAZINONES AS HERBICIDES CYP1B1, CYP1A1, PDXK CA1 2116/4885CA2 1100/4885STAT1 2577/4885
US-20150105252-A1 SUBSTITUTED PYRAZOLES AS HERBICIDES CYP1B1, CYP1A1, DDT CA1 1861/4885CA2 2305/4885STAT1 1860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.