Sugi Predict

Sugi Predict / Compounds / SCHEMBL16632740

SCHEMBL16632740

SCHEMBL16632740

CCOC(=O)c1cnc(-c2ccccc2)n(-c2ccccc2OC)c1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.52
▸ KDM4E B2RXH2 2/20 0.52
▸ LMNA P02545 3/20 0.51
▸ NPSR1 Q6W5P4 2/20 0.51
▸ GLA P06280 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ MEN1 O00255 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ ALDH1A1 P00352 4/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ ATM Q13315 1/20 0.47
▸ GAA P10253 1/20 0.47
▸ HPGD P15428 1/20 0.47
▸ ALOX15 P16050 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47
▸ NPC1 O15118 1/20 0.46
▸ TP53 P04637 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29489592 1.00 MAPT (0.52) MAPTKDM4ELMNANPSR1GLA
SCHEMBL1527905 0.83 MAPT (0.58) MAPTKDM4ELMNAGLAMEN1
SCHEMBL29036869 0.80 TSHR (0.46) MAPTKDM4ELMNAHTTMEN1
SCHEMBL9893973 0.76 NPC1 (0.59) MAPTKDM4ELMNANPSR1MEN1
SCHEMBL7960592 0.75 SMN1; SMN2 (0.60) MAPTKDM4ELMNANPSR1MEN1
SCHEMBL3493632 0.75 ALDH1A1 (0.46) MAPTKDM4ELMNANPSR1ALDH1A1
SCHEMBL9894331 0.74 MAPT (0.56) MAPTKDM4ELMNANPSR1MEN1
SCHEMBL7959390 0.74 KDM4E (0.55) MAPTKDM4ELMNAGLAMEN1
SCHEMBL9894423 0.73 MAPT (0.54) MAPTKDM4ELMNANPSR1MEN1
SCHEMBL7293735 0.73 KDM4E (0.54) MAPTKDM4ELMNAGLAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098020-A1 HERBICIDAL PYRIMIDINYLMETHYL-SUBSTITUTED 1,2,4-TRIAZOLES FMC CORP (US) 2026-04-09 — — US disclosed
EP-4714942-A1 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC Corporation (US) 2026-03-25 — — EP disclosed
US-12552752-B2 Atropisomers of pyridazinone derivatives as herbicides FMC CORPORATION (US) 2026-02-17 — — US disclosed
EP-4188093-B9 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC CORP (US) 2025-12-03 — — EP disclosed
US-12435044-B2 Pyridazinone herbicides and pyridazinone intermediates used to prepare a herbicide FMC CORPORATION (US) 2025-10-07 — — US disclosed
EP-3599868-B1 HERBICIDAL MIXTURE, COMPOSITION AND METHOD FMC CORP (US) 2025-09-24 — — EP disclosed
EP-4188093-B1 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC CORP (US) 2025-09-03 — — EP disclosed
EP-4267556-B1 SUBSTITUTED PYRIDAZINONE HERBICIDES FMC CORP (US) 2025-04-09 — — EP disclosed
EP-4086240-B1 PYRROLIDINONE HERBICIDES FMC CORP (US) 2025-02-05 — — EP disclosed
EP-3094631-B2 PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES FMC CORP (US) 2024-12-25 — — EP disclosed
EP-3073823-A1 STABILIZED LOW-CONCENTRATION METSULFURON-METHYL LIQUID COMPOSITION E. I. du Pont de Nemours and Company (US) 2016-10-05 — — EP disclosed
WO-2016149315-A1 SUBSTITUTED PYRIMIDINYLOXY PYRIDINE DERIVATIVES AS HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2016-09-22 — — WO disclosed
US-9302999-B2 Substituted triazoles as herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2016-04-05 — — US disclosed
US-20160068509-A1 PYRIDAZINONES AS HERBICIDES FMC CORPORATION 2016-03-10 — — US disclosed
WO-2016014814-A1 PYRIDONES AS HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2016-01-28 — — WO disclosed
WO-2015191377-A1 HERBICIDAL SUBSTITUTED 3-ARYLPYRAZOLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2015-12-17 — — WO disclosed
WO-2015168010-A1 PYRIDAZINONE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2015-11-05 — — WO disclosed
US-20150284343-A1 SUBSTITUTED TRIAZOLES AS HERBICIDES FMC CORPORATION 2015-10-08 — — US disclosed
WO-2015077587-A1 STABILIZED LOW-CONCENTRATION METSULFURON-METHYL LIQUID COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2015-05-28 — — WO disclosed
US-20150105252-A1 SUBSTITUTED PYRAZOLES AS HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY 2015-04-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150284343-A1 SUBSTITUTED TRIAZOLES AS HERBICIDES CYP1B1, CYP1A1, CBR3 MAPT 3863/4885KDM4E 2169/4885LMNA 4618/4885
US-12435044-B2 Pyridazinone herbicides and pyridazinone intermediates used to prepare a herbicide CBR3, CBR1, CYP4F3 MAPT 4763/4885KDM4E 3021/4885LMNA 2149/4885
US-12552752-B2 Atropisomers of pyridazinone derivatives as herbicides CBR3, TDO2, FOXO3 MAPT 3434/4885KDM4E 2365/4885LMNA 4256/4885
US-20260098020-A1 HERBICIDAL PYRIMIDINYLMETHYL-SUBSTITUTED 1,2,4-TRIAZOLES CBR3, CBR1, CNPY3 MAPT 4769/4885KDM4E 3034/4885LMNA 2391/4885
US-20160068509-A1 PYRIDAZINONES AS HERBICIDES CYP1B1, CYP1A1, PDXK MAPT 4127/4885KDM4E 1897/4885LMNA 3711/4885
US-20150105252-A1 SUBSTITUTED PYRAZOLES AS HERBICIDES CYP1B1, CYP1A1, DDT MAPT 4596/4885KDM4E 3970/4885LMNA 4176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.