Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30615469 | 0.81 | DAO (0.54) | DAOKDM4ESMN1; SMN2GABRPGABRD | |
| SCHEMBL11552996 | 0.81 | DAO (0.54) | DAOKDM4ESMN1; SMN2GABRPGABRD | |
| SCHEMBL16634626 | 0.80 | HSP90AA1 (0.54) | RORCCYP2C9DAOAURKAKDM4E | |
| SCHEMBL527340 | 0.80 | DAO (0.54) | RORCDAOAURKAKDM4ESMN1; SMN2 | |
| SCHEMBL16634734 | 0.79 | DAO (0.50) | RORCCYP2C9DAOAURKAKDM4E | |
| SCHEMBL11552583 | 0.79 | DAO (0.49) | DAOKDM4EGABRPGABRDGABRA1 | |
| SCHEMBL16634724 | 0.76 | TGFBR1 (0.47) | RORCDAOAURKAKDM4ESMN1; SMN2 | |
| SCHEMBL30615655 | 0.74 | DAO (0.47) | DAOKDM4EGABRPGABRDGABRA1 | |
| SCHEMBL30615525 | 0.74 | PKM (0.45) | DAOKDM4EGABRPGABRDGABRA1 | |
| SCHEMBL30615622 | 0.72 | DAO (0.54) | DAOSMN1; SMN2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |