Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18356855 | 0.80 | ALOX12 (0.67) | ALDH1A1L3MBTL1GAAMAPK1ALOX12 | |
| SCHEMBL26545931 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EL3MBTL1HPGDGAA | |
| SCHEMBL3049191 | 0.71 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EGAAMAPK1ALOX12 | |
| SCHEMBL16646174 | 0.71 | ALOX12 (0.50) | ALDH1A1L3MBTL1GAAMAPK1ALOX12 | |
| SCHEMBL16646117 | 0.71 | ALOX12 (0.66) | ALDH1A1L3MBTL1GAAMAPK1ALOX12 | |
| SCHEMBL2711213 | 0.69 | MAPT (0.68) | ALDH1A1KDM4EL3MBTL1HPGDGAA | |
| SCHEMBL16646175 | 0.68 | ALOX12 (0.52) | ALDH1A1L3MBTL1HPGDGAAMAPK1 | |
| SCHEMBL13212143 | 0.67 | RAB9A (0.65) | ALDH1A1KDM4ELMNASMN1; SMN2PKM | |
| SCHEMBL13873886 | 0.67 | CYP19A1 (0.55) | ALDH1A1KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL1998287 | 0.66 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015054662-A1 | 4-((2-HYDROXY-3-METHOXYBENZYL)AMINO) BENZENESULFONAMIDE DERIVATIVES AS 12-LIPOXYGENASE INHIBITORS | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2015-04-16 | — | — | WO | disclosed |