Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26545860 | 0.81 | HIF1A (0.47) | ALDH1A1KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL16646173 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL18356855 | 0.80 | ALOX12 (0.67) | ALDH1A1L3MBTL1MAPK1LMNAGAA | |
| SCHEMBL26545834 | 0.80 | GAA (0.71) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL26546033 | 0.80 | ALOX12 (0.67) | ALDH1A1L3MBTL1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL26545845 | 0.75 | MAPT (0.47) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL26546062 | 0.74 | ALOX12 (0.54) | ALDH1A1L3MBTL1HPGDSMN1; SMN2ALOX12 | |
| SCHEMBL26546076 | 0.74 | PKM (0.49) | ALDH1A1L3MBTL1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL3049191 | 0.72 | SMN1; SMN2 (0.53) | ALDH1A1KDM4ESMN1; SMN2MAPK1LMNA | |
| SCHEMBL2711213 | 0.71 | MAPT (0.68) | ALDH1A1KDM4EL3MBTL1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054936-B1 | 4-((2-HYDROXY-3-METHOXYBENZYL)AMINO) BENZENESULFONAMIDE DERIVATIVES AS 12-LIPOXYGENASE INHIBITORS | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2023-10-18 | — | — | EP | disclosed |