SCHEMBL166710

SCHEMBL166710

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nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 1/20 0.38
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17489170 1.00 NOS1 (0.38) NOS1TSHR
SCHEMBL166711 1.00 NOS1 (0.38) NOS1TSHR
SCHEMBL14389726 0.79 NOS1 (0.32) NOS1
SCHEMBL347809 0.79
SCHEMBL13053377 0.79 NOS1 (0.32) NOS1
SCHEMBL23960910 0.79
SCHEMBL23829836 0.77
SCHEMBL25481131 0.77
SCHEMBL1094661 0.75
SCHEMBL16439241 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363923-B1 RHODIUM AND IRIDIUM COMPLEXES MERCK PATENT GMBH (DE) 2009-04-01 EP claimed
US-7125998-B2 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2006-10-24 US claimed
EP-1562964-B1 PALLADIUM AND PLATINUM COMPLEXES MERCK PATENT GMBH (DE) 2006-07-19 EP claimed
EP-1562964-A1 PALLADIUM AND PLATINUM COMPLEXES Covion Organic Semiconductors GmbH (DE) 2005-08-17 EP claimed
US-20040138455-A1 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2004-07-15 US claimed
WO-2004041835-A1 PALLADIUM AND PLATINUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-05-21 WO claimed
EP-1363923-A1 RHODIUM AND IRIDIUM COMPLEXES Covion Organic Semiconductors GmbH (DE) 2003-11-26 EP claimed
WO-2002068435-A1 RHODIUM AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2002-09-06 WO claimed
US-12635401-B2 Metal complexes UDC Ireland (IE) 2026-05-19 US disclosed
EP-4069709-B1 METAL COMPLEXES UDC IRELAND LTD (IE) 2025-04-23 EP disclosed
US-12250871-B2 Metal complexes UDC IRELAND LIMITED (IE) 2025-03-11 US disclosed
US-20240260448-A1 Metal Complexes UDC IRELAND LIMITED (IE) 2024-08-01 US disclosed
US-11917901-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-20230056324-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-02-23 US disclosed
US-20050031900-A1 Aromatic monomer-and conjugated polymer-metal complexes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-02-10 US disclosed
US-20040138455-A1 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2004-07-15 US disclosed
WO-2004041835-A1 PALLADIUM AND PLATINUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-05-21 WO disclosed
WO-2004037836-A1 RHODIUM AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-05-06 WO disclosed
EP-1363923-A1 RHODIUM AND IRIDIUM COMPLEXES Covion Organic Semiconductors GmbH (DE) 2003-11-26 EP disclosed
WO-2002068435-A1 RHODIUM AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2002-09-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12635401-B2 Metal complexes SCO2, SOD1, NR4A1 NOS1 1651/4885TSHR 819/4885
US-20040138455-A1 Rhodium and iridium complexes RPIA, MPI, INPP5B NOS1 3525/4885TSHR 2857/4885
US-12250871-B2 Metal complexes AP1M1, SOD1, AP3M1 NOS1 3933/4885TSHR 4537/4885
US-20230056324-A1 METAL COMPLEXES MCU, IMMT, SOD1 NOS1 3890/4885TSHR 3800/4885
US-11917901-B2 Metal complexes MCOLN2, MCOLN1, AP1M1 NOS1 916/4885TSHR 4796/4885
US-20240260448-A1 Metal Complexes SOD1, AP1M1, AP3M1 NOS1 3883/4885TSHR 4496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.