SCHEMBL166723

SCHEMBL166723

O=C(O)Cc1ccc(I)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.62
CAMK2A Q9UQM7 1/20 0.62
AKR1B1 P15121 1/20 0.61
LMNA P02545 2/20 0.58
GAA P10253 2/20 0.58
TSHR P16473 2/20 0.58
ABCC4 O15439 1/20 0.58
PTGS1 P23219 1/20 0.58
HTT P42858 1/20 0.58
ALDH1A1 P00352 3/20 0.52
HPGD P15428 3/20 0.52
HSD17B10 Q99714 3/20 0.52
FFAR1 O14842 1/20 0.52
POLB P06746 2/20 0.50
KDM4E B2RXH2 2/20 0.50
MAPT P10636 2/20 0.50
NSD2 O96028 1/20 0.50
GRK2 P25098 1/20 0.50
CASP6 P55212 1/20 0.50
CTDSP1 Q9GZU7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29674759 1.00 CA2 (0.62) CA2CAMK2AAKR1B1LMNAGAA
Hydrochloric Acid SCHEMBL27999838 0.98 CA2 (0.60) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL5924483 0.88 SRD5A2 (0.62) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL69614 0.87 CA2 (0.79) CA2CAMK2AAKR1B1LMNAGAA
Hydrochloric Acid SCHEMBL25180348 0.84 CA2 (0.75) CA2CAMK2AAKR1B1LMNAGAA
Hydrochloric Acid SCHEMBL6765874 0.84 CA2 (0.75) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL2642144 0.82 CA2 (0.65) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL27740202 0.80 CA2 (0.62) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL18427891 0.79 LMNA (0.86) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL68027 0.79 LMNA (0.86) CA2CAMK2AAKR1B1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 709 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137821-A1 PEPTIDE STRUCTURE TARGETING CARBONIC DEHYDROGENASE IX AND USE THEREOF C-BIOMEX CO., LTD. (KR) 2026-05-21 US claimed
WO-2025023747-A1 PEPTIDE STRUCTURE TARGETING CARBONIC DEHYDROGENASE IX AND USE THEREOF (주)씨바이오멕스 2025-01-30 WO claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
US-20240050599-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES CORNELL UNIVERSITY (US) 2024-02-15 US claimed
US-20230285603-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES CORNELL UNIVERSITY (US) 2023-09-14 US claimed
WO-2023137518-A1 PLATINUM COMPLEXES Western Sydney University (AU) 2023-07-27 WO claimed
US-20230165979-A1 COPPER-CONTAINING THERAGNOSTIC COMPOSITIONS AND METHODS OF USE CORNELL UNIVERSITY (US) 2023-06-01 US claimed
CN-115989042-A Copper-containing theranostic compounds and methods of use 康奈尔大学 2023-04-18 CN claimed
EP-4146236-A1 COPPER-CONTAINING THERAGNOSTIC COMPOUNDS AND METHODS OF USE Cornell University (US) 2023-03-15 EP claimed
WO-2021225760-A1 COPPER-CONTAINING THERAGNOSTIC COMPOUNDS AND METHODS OF USE CORNELL UNIVERSITY (US) 2021-11-11 WO claimed
US-5710178-A ARYL- AND ARYLOXYALKANOIC ACIDS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-01-20 US claimed
US-5708025-A BY INDUCING PRODUCTION OF FETAL HEMOGLOBINS BY ADMINISTERING SPECIFIED ARYL ACIDS, DERIVATIVES, SALTS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-01-13 US claimed
US-5708171-A HISTAMINE H3-RECEPTOR ANTAGONIST INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 1998-01-13 US claimed
US-5661179-A ADMINISTERING; TREATS NEUROBLASTOMA, MYELODYSPLASIA, NON-SMALL CELL LUNG CANCER, PROSTATE CANCER, MELANOMA, BRAIN TUMOR, KAPOSI'S SARCOMA, LYMPHOMA, LEUKEMIA, BREAST AND LUNG CANCER, OSTEOSARCOMA AND FIBROSARCOMA THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1997-08-26 US claimed
US-5654333-A THERAPY FOR ANEMIA, CANCER, AIDS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1997-08-05 US claimed
US-5635532-A ADMINISTERING PHENYL OR NAPHTHYL ACETIC ACID DERIVATIVES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1997-06-03 US claimed
US-5635533-A ANTITUMOR AGENTS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1997-06-03 US claimed
US-5605930-A ADMINISTERING PHENYLACETIC ACID AS AN INHIBITOR OF THE MEVALONATE PATHWAY THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1997-02-25 US claimed
EP-0460111-B1 PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS EASTMAN KODAK CO (US) 1993-12-08 EP claimed
US-4252719-A REMOVAL OF A TERTIARY HYDROGEN FROM A 5-A-STEROID BY CHLORINATING THE STEROID BEING FIRST ESTERIFIED BY AN IODOARYL-CONTAINING ESTERIFICATION AGENT RESEARCH CORPORATION (US) 1981-02-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230285603-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES VHL, GLS, GPER1 CA2 2692/4885CAMK2A 1586/4885AKR1B1 535/4885
US-20240050599-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES VHL, GLS, GPER1 CA2 2692/4885CAMK2A 1586/4885AKR1B1 535/4885
US-20260137821-A1 PEPTIDE STRUCTURE TARGETING CARBONIC DEHYDROGENASE IX AND USE THEREOF CA5A, CA1, CA9 CA2 6/4885CAMK2A 1077/4885AKR1B1 964/4885
US-20230165979-A1 COPPER-CONTAINING THERAGNOSTIC COMPOSITIONS AND METHODS OF USE SHBG, FABP6, SERPINA6 CA2 255/4885CAMK2A 1547/4885AKR1B1 3594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.