SCHEMBL16674288

SCHEMBL16674288

c1ccc(-c2cc(-c3ccccc3)cc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6cccc(-c7ccc8ccccc8c7)c6)c5c43)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 3/20 0.41
HSD17B2 P37059 3/20 0.41
ATM Q13315 2/20 0.39
KDM4E B2RXH2 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ESR1 P03372 4/20 0.36
ESR2 Q92731 4/20 0.36
OPRD1 P41143 2/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36
TUBA3E Q6PEY2 1/20 0.36
TUBA1A Q71U36 1/20 0.36
TUBA1C Q9BQE3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24356678 0.96 HSD17B1 (0.44) HSD17B1HSD17B2ATMKDM4EL3MBTL1
SCHEMBL26348838 0.95 L3MBTL1 (0.45) HSD17B1HSD17B2ATMKDM4EL3MBTL1
SCHEMBL24356545 0.94 L3MBTL1 (0.44) HSD17B1HSD17B2ATMKDM4EL3MBTL1
SCHEMBL23232312 0.94 L3MBTL1 (0.44) HSD17B1HSD17B2ATMKDM4EL3MBTL1
SCHEMBL24356702 0.94 L3MBTL1 (0.44) HSD17B1HSD17B2ATMKDM4EL3MBTL1
SCHEMBL25775165 0.93 L3MBTL1 (0.46) HSD17B1HSD17B2ATMKDM4EL3MBTL1
SCHEMBL23008267 0.92 L3MBTL1 (0.42) HSD17B1HSD17B2ATMKDM4EL3MBTL1
SCHEMBL23233614 0.92 ATM (0.41) HSD17B1HSD17B2ATMKDM4EL3MBTL1
SCHEMBL23233610 0.92 ATM (0.41) HSD17B1HSD17B2ATMKDM4EL3MBTL1
SCHEMBL26785987 0.92 ATM (0.46) ATMKDM4EL3MBTL1OPRD1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3279961-B1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2023-07-19 EP disclosed
US-20200411772-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2020-12-31 US disclosed
US-10340460-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-07-02 US disclosed
US-20180083201-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2018-03-22 US disclosed
EP-3279961-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2018-02-07 EP disclosed
US-20150115240-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-04-30 US disclosed
US-20150115240-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180083201-A1 ORGANIC ELECTROLUMINESCENT ELEMENT ELF3, LAGE3, ILF3 HSD17B1 2152/4885HSD17B2 1297/4885ATM 3581/4885
US-10340460-B2 Organic electroluminescent element EML4, LAGE3, ELOC HSD17B1 2859/4885HSD17B2 1838/4885ATM 3518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.