Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16681375 | 0.95 | PDE3B (0.35) | PDE3BPDE3AP2RX7 | |
| SCHEMBL16681053 | 0.93 | PDE3B (0.32) | PDE3BPDE3AP2RX7 | |
| SCHEMBL16681539 | 0.91 | RXRA (0.33) | ENPP2ATXN2 | |
| SCHEMBL16680952 | 0.89 | P2RX7 (0.32) | P2RX7 | |
| SCHEMBL16681448 | 0.88 | PDE3B (0.34) | PDE3BPDE3AP2RX7ENPP2 | |
| SCHEMBL16681489 | 0.87 | P2RX7 (0.37) | PDE3BPDE3AP2RX7 | |
| SCHEMBL16680833 | 0.86 | ACLY (0.38) | PDE3BPDE3A | |
| SCHEMBL16681558 | 0.85 | P2RX7 (0.40) | P2RX7 | |
| SCHEMBL16689438 | 0.85 | PKM (0.35) | P2RX7 | |
| SCHEMBL16680928 | 0.84 | RXRA (0.32) | ENPP2ATXN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063144-B1 | ANTIPARASITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-09-08 | — | — | EP | disclosed |
| EP-3063144-B1 | ANTIPARASITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-09-08 | — | — | EP | disclosed |
| EP-3733664-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2020-11-04 | — | — | EP | disclosed |
| US-9447084-B2 | Antiparisitic and pesticidal isoxazoline compounds | MERIAL, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| US-9447084-B2 | Antiparisitic and pesticidal isoxazoline compounds | MERIAL, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| EP-3063144-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | Merial, Inc. (US) | 2016-09-07 | — | — | EP | disclosed |
| US-20150126523-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | MERIAL LIMITED (US) | 2015-05-07 | — | — | US | disclosed |
| US-20150126523-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | MERIAL LIMITED (US) | 2015-05-07 | — | — | US | disclosed |
| WO-2015066277-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | MERIAL LIMITED (US) | 2015-05-07 | — | — | WO | disclosed |
| WO-2015066277-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | MERIAL LIMITED (US) | 2015-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126523-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | ACHE, PRDX1, CHRM1 | PDE3B 137/4885PDE3A 212/4885P2RX7 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.