Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16684946 | 0.84 | ALOX5 (0.37) | KDM4EALOX5 | |
| SCHEMBL16685007 | 0.84 | GAA (0.37) | — | |
| SCHEMBL16684943 | 0.80 | HPGD (0.41) | KDM4EHPGD | |
| SCHEMBL21268576 | 0.73 | ALDH1A1 (0.38) | KDM4EHPGDALOX5 | |
| SCHEMBL16684950 | 0.67 | DRD2 (0.41) | KDM4EALOX5 | |
| SCHEMBL13325989 | 0.65 | EGFR (0.35) | — | |
| SCHEMBL16004612 | 0.64 | EGFR (0.37) | — | |
| Hydrochloric Acid SCHEMBL15321017 | 0.62 | EGFR (0.37) | — | |
| SCHEMBL3964364 | 0.62 | EGFR (0.47) | — | |
| SCHEMBL3958089 | 0.62 | EGFR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288946-B1 | 5-HT2C RECEPTOR AGONISTS AND COMPOSITIONS AND METHODS OF USE | ARENA PHARM INC (US) | 2019-08-21 | — | — | EP | disclosed |
| WO-2015066344-A1 | 5-HT2C RECEPTOR AGONISTS AND COMPOSITIONS AND METHODS OF USE | ARENA PHARMACEUTICALS, INC. (US) | 2015-05-07 | — | — | WO | disclosed |