Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12198406 | 0.86 | SIGMAR1 (0.32) | DRD2DRD4GRM2 | |
| SCHEMBL1668932 | 0.84 | FPR2 (0.36) | DRD2DRD4GRM2 | |
| SCHEMBL12198405 | 0.80 | SIGMAR1 (0.35) | DRD2DRD4GRM2 | |
| SCHEMBL1669279 | 0.79 | GPR119 (0.38) | — | |
| SCHEMBL1669050 | 0.78 | FPR2 (0.40) | DRD2DRD4GRM2 | |
| SCHEMBL1668306 | 0.76 | KMT2A (0.43) | DRD2DRD4 | |
| SCHEMBL1670840 | 0.74 | TEAD1 (0.38) | DRD4 | |
| SCHEMBL1670715 | 0.72 | GPR119 (0.41) | — | |
| SCHEMBL12198399 | 0.69 | SIGMAR1 (0.32) | — | |
| SCHEMBL1668609 | 0.68 | FPR2 (0.37) | DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486033-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011044001-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-04-14 | — | — | WO | disclosed |