Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12198367 | 0.85 | ACHE (0.43) | KMT2AMEN1ACHEMCHR1SLC6A4 | |
| SCHEMBL1670849 | 0.84 | CCR3 (0.46) | KMT2AMEN1ACHEMCHR1CCR3 | |
| SCHEMBL1670840 | 0.80 | TEAD1 (0.38) | ACHEMCHR1DRD4 | |
| SCHEMBL1668930 | 0.76 | DRD2 (0.31) | DRD4DRD2 | |
| SCHEMBL1669279 | 0.75 | GPR119 (0.38) | — | |
| SCHEMBL1668670 | 0.71 | HTR2C (0.35) | ACHE | |
| SCHEMBL1669073 | 0.70 | PPARD (0.39) | SLC6A4SLC6A2 | |
| SCHEMBL1670870 | 0.69 | MEN1 (0.42) | KMT2AMEN1ACHESLC6A4SLC6A3 | |
| SCHEMBL12198368 | 0.68 | TSHR (0.44) | KMT2AMEN1ACHEDRD4SLC6A4 | |
| SCHEMBL1670715 | 0.68 | GPR119 (0.41) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486033-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2012-08-15 | — | — | EP | claimed |
| WO-2011044001-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-04-14 | — | — | WO | claimed |