SCHEMBL16689484

SCHEMBL16689484

CC(C)(C)OC(=O)C(CC(=O)O)NC(=O)OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 16/20 0.59
SYK P43405 1/20 0.58
CTSK P43235 2/20 0.55
CTSL P07711 1/20 0.54
CTSB P07858 1/20 0.54
CTSS P25774 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45447 1.00 CASP1 (0.59) CASP1SYKCTSKCTSLCTSB
SCHEMBL2619551 1.00 CASP1 (0.59) CASP1SYKCTSKCTSLCTSB
SCHEMBL30947821 0.92 CASP1 (0.62) CASP1SYKCTSLCTSBCTSS
SCHEMBL13324038 0.92 CTSL (0.58) CTSKCTSLCTSBCTSS
SCHEMBL14385711 0.90 SYK (0.56) CASP1SYKCTSKCTSLCTSB
SCHEMBL6078490 0.90 SYK (0.56) CASP1SYKCTSKCTSLCTSB
SCHEMBL6078485 0.90 SYK (0.56) CASP1SYKCTSKCTSLCTSB
SCHEMBL5033775 0.90 PPARA (0.58) CASP1SYKCTSKCTSLCTSB
SCHEMBL1093029 0.90 PPARA (0.58) CASP1SYKCTSKCTSLCTSB
SCHEMBL3004720 0.90 PPARA (0.58) CASP1SYKCTSKCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 US disclosed
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 US disclosed
US-20240409580-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-12 US disclosed
US-12139554-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-11-12 US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 US disclosed
WO-2024043313-A1 REVERSIBLE THERMOCHROMIC COMPOSITION, MICROENCAPSULATED PIGMENT USING SAID REVERSIBLE THERMOCHROMIC COMPOSITION, WRITING TOOL, AND TOY 三菱ケミカル株式会社 2024-02-29 WO disclosed
CN-116327950-A Use of a composition for the treatment of neuropsychiatric symptoms of neurodegenerative diseases 阿泽范药品公司 2023-06-27 CN disclosed
US-20230174562-A1 RADIO-AND CHEMO-PROTECTIVE COMPOUNDS Tonix Pharmaceuticals, Inc. 2023-06-08 US disclosed
CN-116139282-A Compositions and methods for treating neurodegenerative diseases 阿泽范药品公司 2023-05-23 CN disclosed
US-10123985-B2 Therapeutic strategies for treating mitochondrial disorders WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2018-11-13 US disclosed
US-20180258134-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2018-09-13 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-20180000952-A1 ENZYME AND RECEPTOR MODULATION CHROMA THERAPEUTICS LIMITED (GB) 2018-01-04 US disclosed
US-20160354332-A1 THERAPEUTIC STRATEGIES FOR TREATING MITOCHONDRIAL DISORDERS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-12-08 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
US-20150126534-A1 ENZYME AND RECEPTOR MODULATION GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2015-05-07 US disclosed
CN-101541800-A Pteridine derivatives as polo-like kinase inhibitors useful in the treatment of cancer CHROMA THERAPEUTICS LTD (GB) 2009-09-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 CASP1 4534/4885SYK 4321/4885CTSK 889/4885
US-10123985-B2 Therapeutic strategies for treating mitochondrial disorders GOT2, GOT1, OTC CASP1 1698/4885SYK 4806/4885CTSK 3711/4885
US-20230174562-A1 RADIO-AND CHEMO-PROTECTIVE COMPOUNDS MGMT, RCOR3, TSPO CASP1 99/4885SYK 4867/4885CTSK 1976/4885
US-20180000952-A1 ENZYME AND RECEPTOR MODULATION CES1, HCAR1, DNPEP CASP1 2960/4885SYK 1716/4885CTSK 723/4885
US-20180258134-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 CASP1 4534/4885SYK 4321/4885CTSK 889/4885
US-20240409580-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 CASP1 4534/4885SYK 4321/4885CTSK 889/4885
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 CASP1 3525/4885SYK 4434/4885CTSK 824/4885
US-12139554-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 CASP1 4534/4885SYK 4321/4885CTSK 889/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 CASP1 4037/4885SYK 4295/4885CTSK 965/4885
US-20150126534-A1 ENZYME AND RECEPTOR MODULATION CES1, HCAR1, DNPEP CASP1 2960/4885SYK 1716/4885CTSK 723/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 CASP1 4534/4885SYK 4321/4885CTSK 889/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 CASP1 4534/4885SYK 4321/4885CTSK 889/4885
US-20160354332-A1 THERAPEUTIC STRATEGIES FOR TREATING MITOCHONDRIAL DISORDERS GOT2, GOT1, OTC CASP1 1698/4885SYK 4806/4885CTSK 3711/4885
US-20160304555-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 CASP1 4534/4885SYK 4321/4885CTSK 889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.